Clinical Trials

Phase 2 Active not recruiting

115 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT03678883 2026-04-03

9-ING-41 in Patients With Advanced Cancers

350 enrolled

BreastCNSGastrointestinalGenitourinaryLymphoidOther hematologic neoplasmSarcomaThoracic

Bone Neoplasms, Breast Neoplasms, Glioma, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Non-Hodgkin, Neoplasm Metastasis, Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Pancreatic Neoplasms, Sarcoma, Colorectal Neoplasms, Leukemia-Lymphoma, Adult T-Cell

NCT07477457 2026-03-17

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

45 enrolled

LymphoidMyeloidOther hematologic neoplasm

Neoplasm Metastasis, Osteosarcoma

NCT05292664 2026-03-12

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Phase 1 Recruiting

30 enrolled

Myelodysplastic Syndromes, Neoplasm Metastasis, Recurrence, Leukemia, Biphenotypic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04329494 2025-12-10

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Phase 1 Recruiting

49 enrolled

GastrointestinalGynecologic

Appendiceal Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT04874311 2025-08-13

TRUST

80 enrolled

BreastDermatologicGenitourinaryGynecologicThoracic

Tertiary Lymphoid Structures, Neoplasm Metastasis, Sarcoma

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT05824975 2024-11-25

A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)

Phase 1/2 Recruiting

358 enrolled

DermatologicGastrointestinalGenitourinarySarcoma

Diabetes Mellitus, Insulin-Dependent, 12, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Melanoma, Neoplasm Metastasis, Sarcoma, Colorectal Neoplasms

NCT01678664 2024-09-25

EVACEL

74 enrolled 10 charts

EndocrineNET

Neoplasm Metastasis, Neoplasms, Neuroendocrine Tumors

NCT02049905 2024-06-13

Phase 3 Study to Treat Patients With Soft Tissue Sarcomas

Phase 3 Completed

433 enrolled 10 charts

Neoplasm Metastasis, Sarcoma

NCT01514188 2024-05-29

Preliminary Efficacy and Safety of INNO-206 Compared to Doxorubicin in Advanced Soft Tissue Sarcoma

126 enrolled 13 charts

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

Neoplasm Metastasis, Sarcoma

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Phase 1 Terminated

2 enrolled

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT00003907 2023-07-05

Chemoembolization in Treating Patients With Primary Liver Cancer or Metastases to the Liver

50 enrolled 8 charts

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis

NCT02499367 2022-03-22

TONIC

Phase 2 Unknown

84 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT04159818 2022-03-22

TONIC-2

52 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00023868 2020-12-02

Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655)

Phase 3 Terminated

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT02677116 2020-05-20

A Study of Olaratumab Alone and in Combination With Standard Chemotherapies in Children With Cancer

68 enrolled 26 charts

Tumor-Agnostic

Neoplasm Metastasis

NCT03804866 2019-01-15

NGR-hTNF in Combination With an Anthracycline in Platinum-resistant Ovarian Cancer (NGR018)

14 enrolled

Gynecologic

Neoplasm Metastasis, Ovarian Neoplasms, Disease Progression

NCT00080782 2018-10-31

Doxorubicin and Strontium-89 With or Without Celecoxib in Treating Patients With Progressive Androgen-Independent Prostate Cancer and Bone Metastases

14 enrolled

Genitourinary

Neoplasm Metastasis, Prostatic Neoplasms

NCT01358071 2018-09-27

NGR018

119 enrolled

Gynecologic

Neoplasm Metastasis, Ovarian Neoplasms, Disease Progression

NCT00804830 2018-08-28

Avastin and Doxorubicin Postoperatively for Patients With Anaplastic Thyroid Cancer

15 enrolled

EndocrineHead & Neck

Carcinoma, Neoplasm Metastasis, Thyroid Neoplasms, Thyroid Carcinoma, Anaplastic

NCT00730483 2017-08-25

Doxorubicin Beads in Treating Patients With Unresectable Liver Metastases From Neuroendocrine Tumors

Phase NA Terminated

13 enrolled 5 charts

Endocrine

Glucagonoma, Insulinoma, Adenoma, Islet Cell, Neoplasm Metastasis, Somatostatinoma, Gastrinoma, Carcinoma, Islet Cell

NCT00609765 2017-03-23

Avastin, Fluorouracil, Doxorubicin and Streptozocin in Locally Advanced and Metastatic Pancreatic Endocrine Tumors

1 enrolled 3 charts

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT00081159 2016-11-10

Hormone Ablation Therapy, Doxorubicin, and Zoledronate With or Without Strontium 89 in Treating Patients With Androgen-Dependent Prostate Cancer and Bone Metastases

80 enrolled 6 charts

Genitourinary

Neoplasm Metastasis, Prostatic Neoplasms

NCT01815294 2015-12-04

A Pivotal Bioequivalence Study of DOXIL/CAELYX (Doxorubicin HCL) in Patients With Advanced or Refractory Solid Malignancies Including Patients With Ovarian Cancer

54 enrolled

BreastGynecologic

Breast Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms

NCT01703910 2015-10-09

Study of Individualized Therapies Selection for Patients With Metastatic Colorectal Carcinoma According to the Therapeutic

29 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms

NCT00377559 2015-10-06

MYOTAX

70 enrolled

Breast Neoplasms, Neoplasm Metastasis, Cardiotoxicity

NCT00377780 2015-09-23

MYOHERTAX

60 enrolled

Breast Neoplasms, Neoplasm Metastasis, Cardiotoxicity

NCT00798252 2015-07-07

Ascending Multiple-Dose Study of Brivanib Alaninate in Combination With Chemotherapeutic Agents in Subjects With Advanced Cancers

111 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT00626704 2015-05-25

Phase 1b/2 Study of AMG 655 With Doxorubicin for the First-Line Treatment of Unresectable Soft Tissue Sarcoma

Phase 1/2 Completed

134 enrolled

Neoplasm Metastasis, Sarcoma

NCT00176293 2015-04-21

Randomized Phase II Trial of Doxil With or Without Dexamethasone for Metastatic Hormone Refractory Prostate Cancer

2 enrolled

Genitourinary

Neoplasm Metastasis, Prostatic Neoplasms

NCT00795678 2013-08-02

Chemotherapeutic Agents in Brain/Breast

Completed

10 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis

NCT01168791 2013-07-18

PICASSO III

Phase 3 Completed

447 enrolled

Neoplasm Metastasis, Sarcoma

NCT00004930 2013-06-19

Inhaled Doxorubicin in Treating Patients With Primary Lung Cancer or Lung Metastases