Clinical Trials Browser

Interventional × Neoplasm Metastasis × Everolimus × Clear all

NCT04802759 2026-04-13

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

Phase 1/2 Recruiting

Neoplasm Metastasis

NCT06943755 2026-03-24

STELLAR-311

Phase 2/3 Recruiting

Adenoma, Islet Cell, Neoplasm Metastasis, Neuroendocrine Tumors

NCT05933395 2026-01-20

GERTRUDE

Phase 2 Recruiting

Neoplasm Metastasis

NCT03065387 2026-01-12

Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

Phase 1 Active not recruiting

Neoplasm Metastasis

NCT02321501 2025-11-10

Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer

Phase 1 Active not recruiting

Neoplasm Metastasis

NCT01582191 2025-10-27

Vandetanib and Everolimus in Treating Patients With Advanced or Metastatic Cancer

Phase 1 Completed

Neoplasm Metastasis, Neoplasms, Recurrence

NCT02029001 2025-08-07

MOST plus

Phase 2 Recruiting

Neoplasm Metastasis

NCT00640978 2025-05-01

Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer

Phase 2 Terminated

16 enrolled 4 charts

Gastrointestinal

Neoplasm Metastasis, Pancreatic Neoplasms

NCT00317720 2025-04-30

Trastuzumab and RAD001 in Patients With Human Epidermal Growth Receptor 2 (HER-2) Overexpressing Breast Cancer

Phase 1/2 Completed

40 enrolled 8 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00253318 2025-04-27

RAD001 Plus Docetaxel in Patients With Metastatic Breast Cancer

Phase 1 Terminated

Breast Neoplasms, Neoplasm Metastasis

NCT05188118 2024-11-06

Rapid Sequencing of Approved Therapies in Patients with Metastatic or Unresectable Clear Cell Renal Cell Carcinoma

Phase EARLY_PHASE1 Recruiting

Carcinoma, Renal Cell, Neoplasm Metastasis

NCT01678664 2024-09-25

EVACEL

Phase 2 Completed

74 enrolled 10 charts

Neoplasm Metastasis, Neoplasms, Neuroendocrine Tumors

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Phase 1 Terminated

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT02915783 2023-01-17

A Trial to Evaluate Efficacy and Safety of Lenvatinib in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Non Clear Cell Renal Cell Carcinoma (nccRCC) Who Have Not Received Any Chemotherapy for Advanced Disease

Phase 2 Completed

41 enrolled 11 charts

Neoplasm Metastasis

NCT00830895 2022-11-09

RAD001 for Non-clear Cell Renal Cell Carcinoma (RCC)

Phase 2 Completed

Carcinoma, Renal Cell, Neoplasm Metastasis

NCT01668784 2022-08-09

Study of Nivolumab (BMS-936558) vs. Everolimus in Pre-Treated Advanced or Metastatic Clear-cell Renal Cell Carcinoma (CheckMate 025)

Phase 3 Completed

821 enrolled 18 charts

Carcinoma, Renal Cell, Neoplasm Metastasis

NCT04355858 2022-07-26

MULAN

Phase 2 Unknown

Breast Neoplasms, Neoplasm Metastasis

NCT01499160 2022-02-11

Letrozole and Lapatinib Followed by Everolimus in Women With Advanced Breast Cancer

Phase 2 Terminated

7 enrolled 6 charts

Breast Diseases, Breast Neoplasms, Neoplasm Metastasis

NCT01783444 2021-02-26

BOLERO-6

Phase 2 Completed

309 enrolled 19 charts

Breast Neoplasms, Neoplasm Metastasis

NCT01624766 2021-02-25

Everolimus and Anakinra or Denosumab in Treating Participants With Relapsed or Refractory Advanced Cancers

Phase 1 Completed

Neoplasm Metastasis, Neoplasms, Recurrence

NCT01197170 2021-01-22

Hormone Receptor Positive Disease Across Solid Tumor Types: A Phase I Study of Single-Agent Hormone Blockade and Combination Approaches With Targeted Agents to Provide Synergy and Overcome Resistance

Phase 1 Completed

Neoplasm Metastasis

NCT00426530 2020-12-21

Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer

Phase 1 Completed

Breast Neoplasms, Neoplasm Metastasis

NCT01190241 2020-11-20

TSAP

Phase NA Terminated

Neoplasm Metastasis

NCT02138929 2020-06-11

LDE225 + Everolimus in Advanced Gastroesophageal Adenocarcinoma

Phase 1 Completed

Gastrointestinal

Esophageal Neoplasms, Neoplasm Metastasis

NCT02109913 2019-10-14

Analysis of Tumor Tissue and Circulating Genetic Material in the Blood to Obtain Further Insight in the Effectiveness of Everolimus When Combined With Exemestane

Phase NA Unknown

Breast Neoplasms, Neoplasm Metastasis

NCT01648465 2019-09-03

Study of Everolimus Treatment in Newly-diagnosed Patients With Advanced Gastrointestinal Neuroendocrine Tumors

Phase 2 Terminated

Gastrointestinal

Digestive System Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms

NCT02142036 2019-03-13

MetAction

Phase 2 Completed

Neoplasm Metastasis

NCT01115803 2019-02-05

A Study of LY2584702 With Erlotinib or Everolimus in Participants With Solid Tumors

Phase 1 Terminated

29 enrolled 19 charts

EndocrineGenitourinaryNETThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Neoplasm Metastasis, Neuroendocrine Tumors

NCT00876395 2018-12-19

BOLERO-1

Phase 3 Completed

719 enrolled 25 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00529802 2018-04-25

Exploratory Study Evaluating Fluorodeoxyglucose - Position Emission Tomography as a Predictive Marker for Therapy With RAD001 in Metastatic Renal Cell Cancer

Phase 2 Completed

60 enrolled 9 charts

Carcinoma, Carcinoma, Renal Cell, Neoplasm Metastasis, Neoplasms

NCT01107509 2018-04-04

Pilot Study of Neo-Adjuvant Everolimus to Treat Advanced Renal Cell Carcinoma - Analysis of Biomarkers

Phase NA Completed

Carcinoma, Renal Cell, Neoplasm Metastasis

NCT02248571 2017-11-13

IMPROVE

Phase 4 Completed

Breast Neoplasms, Neoplasm Metastasis

NCT01784978 2017-10-02

SUNRISES

Phase 2 Terminated

Margins of Excision, Carcinoma, Renal Cell, Neoplasm Metastasis, Neoplasms

NCT01122199 2017-05-10

Study of RAD001 + AMG479 for Patients With Advanced Solid Tumors

Phase 1 Completed

Neoplasm Metastasis

NCT00574769 2017-04-11

Safety Study & Effectiveness of Docetaxel With RAD001 and Bevacizumab in Men With Advanced Prostate Cancer

Phase 1/2 Completed

Neoplasm Metastasis, Prostatic Neoplasms

NCT01283789 2017-02-08

Lapatinib and RAD-001 for HER2 Positive Metastatic Breast Cancer

Phase 2 Unknown

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT02404051 2016-06-15

FEVEX

Phase 3 Unknown

Breast Neoplasms, Neoplasm Metastasis

NCT00459186 2016-05-16

The Use of RAD001 With Docetaxel in the Treatment of Metastatic, Androgen Independent Prostate Cancer

Phase 1/2 Completed

19 enrolled 6 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT01099527 2015-12-29

A Trial of RAD001/Capecitabine in Refractory Gastric Cancer

Phase 1/2 Completed

Gastrointestinal

Neoplasm Metastasis, Stomach Neoplasms

NCT00426556 2015-12-28

Efficacy and Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer

Phase 1 Completed

88 enrolled 10 charts

Breast Neoplasms, Neoplasm Metastasis

NCT02450175 2015-05-21

Etiology of the Platelet-Cancer Metastatic Pathway - A Study of Inflammatory Markers, Platelet Characteristics and Metastatic Surrogates in Cancer Patients and Controls

Phase NA Unknown

Neoplasm Metastasis, Neoplasms

NCT01960829 2015-05-01

Everolimus in Selected Patients With Metastatic Melanoma: Efficacy and Safety Study

Phase 2 Unknown

Melanoma, Neoplasm Metastasis

NCT01178151 2015-04-22

EVAMP

Phase 2 Withdrawn

Neoplasm Metastasis, Neoplasms, Neoplastic Processes, Peutz-Jeghers Syndrome

NCT00384969 2014-08-18

Sorafenib and RAD001 Renal Cell Carcinoma

Phase 1 Completed

Carcinoma, Renal Cell, Neoplasm Metastasis

NCT01127763 2014-04-09

RAD001 Plus Carboplatin in Breast Cancer Patients

Phase 2 Completed

25 enrolled 9 charts

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT01932177 2013-08-30

EVESOR

Phase 1 Unknown

Neoplasm Metastasis

NCT00892801 2012-03-12

Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer

Phase 1 Terminated

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00337545 2007-10-10

Phase II Trial of RAD001 in Refractory Colorectal Cancer

Phase 2 Completed

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms