Clinical Trials

Esophageal Neoplasms, Neoplasm Metastasis, Neoplasms

NCT02029001 2025-08-07

MOST plus

Phase 2 Recruiting

900 enrolled

Neoplasm Metastasis

NCT01300962 2023-12-04

Study of BKM120 or BYL719 and Capecitabine in Patients With Metastatic Breast Cancer

47 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00807859 2022-11-08

Safety Study of AMG 386 to Treat HER2-positive Locally Recurrent or Metastatic Breast Cancer

65 enrolled

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT01499160 2022-02-11

Letrozole and Lapatinib Followed by Everolimus in Women With Advanced Breast Cancer

7 enrolled 6 charts

Breast Diseases, Breast Neoplasms, Neoplasm Metastasis

NCT02650752 2021-01-26

Intermittent High-Dose Lapatinib in Tandem With Capecitabine for HER2 Overexpressed/Amplified Metastatic Breast Cancer With Central Nervous System (CNS) Metastases

11 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT01471847 2020-12-09

A Phase Ib/II Study of BEZ235 and Trastuzumab in Patients With HER2-positive Breast Cancer Who Failed Prior to Trastuzumab

5 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT01190241 2020-11-20

TSAP

Phase NA Terminated

45 enrolled

Neoplasm Metastasis

NCT00367471 2020-09-09

Combination Of Lapatinib With Carboplatin, Paclitaxel, and With or Without Trastuzumab In Metastatic Breast Cancer.

31 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT01118975 2019-11-13

GCC 0845:Vorinostat and Lapatinib in Advanced Solid Tumors and Advanced Breast Cancer to Evaluate Response and Biomarkers

Phase 1/2 Terminated

12 enrolled 6 charts

Breast Neoplasms, Neoplasm Metastasis

NCT02142036 2019-03-13

MetAction

50 enrolled

Neoplasm Metastasis

NCT00777101 2018-08-09

Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast Cancer

233 enrolled 16 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00073008 2017-02-28

A Study Of Oral GW572016 In Advanced Or Metastatic Non-Small Cell Lung Cancer

131 enrolled 14 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT01283789 2017-02-08

Lapatinib and RAD-001 for HER2 Positive Metastatic Breast Cancer

Phase 2 Unknown

23 enrolled

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT02238509 2016-06-15

Safety and QoL of Trastuzumab With Lapatinib or Chemiotherapy in MBC and HER2+ Patients Refractory to Anti HER2 Therapies

Phase 2 Unknown

154 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00338247 2016-04-06

EAP (Expanded Access Protocol) Of Lapatinib Combined With Capecitabine In Metastatic Breast Cancer

Approved for marketing

Breast Neoplasms, Neoplasm Metastasis

NCT00347919 2016-02-25

Pazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Advanced Or Metastatic Breast Cancer

189 enrolled 15 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00526669 2016-01-29

Study For Patients With Untreated Gastric Cancer Who Will Receive Capecitabine And Lapatinib

68 enrolled 16 charts

Neoplasm Metastasis, Neoplasms, Stomach Neoplasms

NCT01985893 2016-01-14

THOR

Phase 2 Withdrawn

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT01087983 2015-11-11

Lapatinib With Sirolimus or Metformin

111 enrolled

Phase EARLY_PHASE1 Terminated

Neoplasm Metastasis

NCT01427322 2015-07-08

Randomized RT +/- Lapatinib for Advanced Solid Tumor Cancer Patients Receiving Radiation Therapy for Metastatic Disease

6 enrolled

Neoplasm Metastasis

NCT00044343 2014-07-10

GW572016, An Oral Drug For Colorectal Cancer Patients Having Prior Therapy With 5-FU Plus CPT-11 And/Or Oxaliplatin

80 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT00544804 2014-07-02

Lapatinib in Treating Patients With Advanced or Metastatic Breast Cancer That Overexpresses HER2

41 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00795678 2013-08-02

Chemotherapeutic Agents in Brain/Breast

Completed

10 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis

NCT00967031 2013-01-18

Lapatinib Ditosylate and Capecitabine in Treating Patients With Stage IV Breast Cancer and Brain Metastases

45 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Breast Neoplasms, Male

NCT00657137 2012-03-15

APRiCOT-B

12 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00078572 2010-12-13

Capecitabine (XELODA) With Or Without Lapatinib (GW572016) For Women With Refractory Advanced or Metastatic Breast Cancer

Phase 3 Completed

408 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00239200 2008-07-30

Lapatinib (GW572016) for Metastatic or Recurrent Squamous Cell Carcinoma Esophagus

29 enrolled