Clinical Trials

BreastDermatologicGenitourinaryGynecologicThoracic

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT06897644 2025-05-25

PANThEON

Phase 3 Recruiting

340 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT00059930 2025-03-26

Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer

38 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT02842580 2024-07-10

HIGH-LIGHT

21 enrolled 12 charts

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Phase 1 Terminated

2 enrolled

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT04617457 2024-01-12

HOLIPANC

Phase 2 Unknown

150 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT03783936 2023-12-19

Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas

18 enrolled 16 charts

Adenocarcinoma Of Esophagus, Neoplasm Metastasis

NCT01718873 2023-04-12

OBELICS

Phase 3 Completed

230 enrolled 12 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT00936832 2022-08-30

Sunitinib Malate and Combination Chemotherapy as Front-Line Therapy in Treating Patients With Metastatic Rectal Cancer That Cannot Be Removed by Surgery

Phase 2 Withdrawn

Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT02080221 2022-08-01

BrUOG 292: FOLFOX-A For Metastatic Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial

50 enrolled 10 charts

Neoplasm Metastasis, Pancreatic Neoplasms

NCT02384850 2022-04-08

SENTINEL

Phase 1 Terminated

10 enrolled 13 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT01442649 2022-01-11

Efficacy of Chemotherapy, Associated to Either Cetuximab or Bevacizumab, in KRAS Wild-type Metastatic Colorectal Cancer Patients With Progressive Disease After Receiving First-line Treatment With Bevacizumab

133 enrolled

Adenocarcinoma, Neoplasm Metastasis, Colorectal Neoplasms

NCT00591123 2021-10-01

Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia

38 enrolled 14 charts

Adenocarcinoma Of Esophagus, Neoplasm Metastasis

NCT01276379 2021-07-02

POSIBA

221 enrolled 17 charts

Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies, Colorectal Neoplasms

NCT03142516 2021-06-21

OPALO

20 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT02128243 2021-03-26

MATEO

242 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Neoplasm Metastasis, Stomach Neoplasms

NCT00005944 2021-02-17

Second-look Surgery With or Without Intraperitoneal Chemotherapy in Treating Patients With Recurrent Colorectal Cancer

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00006050 2021-02-17

Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT01652976 2021-01-05

FOLFOX-D

44 enrolled 18 charts

Adenocarcinoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT01485744 2020-08-04

LDE225 With Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan for Untreated Advanced Pancreatic Cancer

39 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT01206530 2019-04-18

FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer

Phase 1/2 Completed

50 enrolled

Adenocarcinoma, Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms

NCT01996306 2019-01-08

AXEPT

Phase 3 Completed

650 enrolled

Digestive System Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT01888978 2018-04-09

Molecularly Tailored Therapy for Pancreas Cancer

19 enrolled

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT03303495 2017-10-06

A Study of 2nd-line FOLFIRI ± Bevacizumab vs. Irinotecan ± Bevacizumab in mCRC

Phase 3 Unknown

280 enrolled

Digestive System Neoplasms, Gastrointestinal Neoplasms, Intestinal Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT01571024 2017-04-26

BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancer

17 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT00002842 2017-04-11

Liver Resection and Floxuridine Plus Fluorouracil and Leucovorin in Treating Patients With Liver Metastases From Colorectal Cancer

49 enrolled 5 charts

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00227019 2017-03-06

Phase 2 Trial of Bevacizumab in Combination With Pemetrexed

16 enrolled 9 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00056030 2017-01-24

Combination Chemotherapy Plus Cetuximab in Treating Patients With Liver Metastases From Colorectal Cancer

73 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00537823 2016-12-20

Pre- and Post-operative FOLFOX Based Therapy for Patients With Colorectal Cancer With Liver Involvement

9 enrolled 12 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT01322815 2016-08-15

A Pilot Trial of GI-4000 Plus Bevacizumab and Either FOLFOX or FOLFIRI

11 enrolled 8 charts

Colonic Neoplasms, Neoplasm Metastasis

NCT02855788 2016-08-04

Metronomic Chemotherapy in Advanced Gastric Cancer

Phase 2 Unknown

40 enrolled

Neoplasm Metastasis, Stomach Neoplasms

NCT00002716 2016-07-13

Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer

Phase 3 Completed

135 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00003834 2016-07-06

Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer

44 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT02785146 2016-06-08

Adjuvant Chemotherapy Combined With Huaier Granule for Treating High-risk Stage II, Stage III Colorectal Cancer

Phase 3 Unknown

230 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT01183663 2016-06-03

Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)