Clinical Trials Browser

Interventional × Neoplasm Metastasis × NVP-BKM120 × Clear all

Neoplasm Metastasis, Endometrial Neoplasms

NCT01285466 2020-12-09

A Trial of Oral BEZ235 and BKM120 in Combination With Paclitaxel With or Without Trastuzumab

Phase 1 Completed

110 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT01629615 2020-10-28

A Trial of BKM120 (a PI3K Inhibitor) in Patients With Triple Negative Metastatic Breast Cancer

Phase 2 Completed

50 enrolled 10 charts

Breast

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT01610284 2020-08-25

BELLE-2

Phase 3 Completed

1,147 enrolled 20 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT01737450 2019-06-24

PIK-ORL

Phase 2 Completed

58 enrolled

Head & Neck

Head and Neck Neoplasms, Neoplasm Metastasis, Recurrence, Disease Progression

NCT01741753 2019-02-05

BKM120+Abiraterone Acetate for Metastatic CRPC

Phase 1 Terminated

4 enrolled

Genitourinary

Neoplasm Metastasis, Prostatic Neoplasms

NCT01633060 2019-01-30

BELLE-3

Phase 3 Terminated

432 enrolled 20 charts

Breast

Breast Neoplasms, Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies

NCT01790932 2019-01-23

BKM120 For Triple Negative Breast Cancer

Phase 2 Completed

50 enrolled 8 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT01911325 2018-08-14

Phase II Study of Buparlisib + Docetaxel in Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) Patients

Phase 1 Terminated

27 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT01852292 2018-07-24

Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy

Phase 2 Terminated

157 enrolled 22 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT01385293 2017-05-19

BKM120 in Metastatic Castration-resistant Prostate Cancer

Phase 2 Terminated

30 enrolled 11 charts

Genitourinary

Neoplasm Metastasis, Prostatic Neoplasms

NCT02452294 2017-05-03

BUMPER

Phase 2 Unknown

22 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis

NCT01571024 2017-04-26

BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancer

Phase 1 Completed

17 enrolled

Gastrointestinal

Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT01572727 2017-03-09

BELLE-4

Phase 2/3 Completed

416 enrolled 11 charts

Breast

Breast Neoplasms, Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies

NCT02035124 2016-02-11

Cabazitaxel and BKM120 in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel

Phase 2 Withdrawn

Tumor-Agnostic

Neoplasm Metastasis

Clinical Trials

ENDOPIK

A Trial of Oral BEZ235 and BKM120 in Combination With Paclitaxel With or Without Trastuzumab

A Trial of BKM120 (a PI3K Inhibitor) in Patients With Triple Negative Metastatic Breast Cancer

BELLE-2

PIK-ORL

BKM120+Abiraterone Acetate for Metastatic CRPC

BELLE-3

BKM120 For Triple Negative Breast Cancer

Phase II Study of Buparlisib + Docetaxel in Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) Patients

Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy

BKM120 in Metastatic Castration-resistant Prostate Cancer

BUMPER

BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancer

BELLE-4

Cabazitaxel and BKM120 in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel