Clinical Trials

Phase 1 Active not recruiting

2,900 enrolled

Gynecologic

Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Endometrial Neoplasms

NCT06607185 2026-05-26

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

750 enrolled

GastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07432295 2026-05-14

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

180 enrolled

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Adenocarcinoma Of Esophagus, Neoplasm Metastasis, Stomach Neoplasms

NCT05919264 2026-05-12

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Phase 1/2 Recruiting

595 enrolled

Craniopharyngioma, Carcinoma, Hepatocellular, Neoplasm Metastasis, Neoplasms, Adenomatous Polyposis Coli, Prostatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Desmoid Tumors

NCT05611034 2026-04-29

In Vivo Lung Perfusion (IVLP) for Colorectal Cancer Metastatic to Lung

Phase 1 Recruiting

10 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT06846346 2026-04-28

GRACIE

88 enrolled

Adenocarcinoma Of Esophagus, Adenocarcinoma, Neoplasm Metastasis, Neoplasms

NCT05382559 2026-04-14

A Study of ASP3082 in Adults With Advanced Solid Tumors

Phase 1 Recruiting

681 enrolled

Neoplasm Metastasis, Neoplasms

NCT06538623 2026-03-24

Oxaliplatin Combined With Irinotecan Liposome Injection II Through Hepatic Artery Infusion (HAIC) Followed by 5-FU/LV (HAIC) or Tegorgor Oral Combination Therapy for Hepatic Metastasis of Pancreatic Cancer

40 enrolled

Phase 4 Not yet recruiting

Neoplasm Metastasis, Pancreatic Neoplasms

NCT07446465 2026-03-03

FOLFOX Chemotherapy Combined With Fruquintinib and Serplulimab as First-Line Conversion Therapy for Initially Unresectable pMMR/MSS Colorectal Cancer

42 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT03388190 2026-02-13

METIMMOX

80 enrolled 13 charts

Phase 2 Active not recruiting

Neoplasm Metastasis, Neoplasms

NCT06268015 2026-02-05

BBOpCo

16 enrolled

GastrointestinalGynecologic

Neoplasm Metastasis, Colorectal Neoplasms

NCT04329494 2025-12-10

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Phase 1 Recruiting

49 enrolled

Appendiceal Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Peritoneal Neoplasms, Stomach Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT00492999 2025-08-17

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Phase 2 Active not recruiting

64 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00680901 2025-08-07

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

Phase 3 Completed

545 enrolled 24 charts

Esophageal Neoplasms, Neoplasm Metastasis, Neoplasms

NCT02885753 2025-07-09

OSCAR

Phase 3 Recruiting

348 enrolled

BreastDermatologicGenitourinaryGynecologicThoracic

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

Phase 1 Terminated

221 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT06897644 2025-05-25

PANThEON

Phase 3 Recruiting

340 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT02795988 2025-04-16

A Study of IMU-131(HER-Vaxx) and Chemotherapy Compared to Chemotherapy Only in Patients With HER2 Positive Advanced Gastric Cancer

Phase 1/2 Completed

64 enrolled 20 charts

Adenocarcinoma, Gastrointestinal Neoplasms, Neoplasm Metastasis

NCT00059930 2025-03-26

Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer

Phase 1 Completed

38 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT03009058 2024-11-25

MODULATE

Phase 1/2 Terminated

2 enrolled 7 charts

DermatologicSarcoma

Melanoma, Neoplasm Metastasis, Sarcoma

NCT05476796 2024-10-24

LOGICAN

118 enrolled

Adenocarcinoma Of Esophagus, Adenocarcinoma, Neoplasm Metastasis, Recurrence

NCT02848443 2024-07-25

Study of S 95005 in Combination With Oxaliplatin in Metastatic Colorectal Cancer

Phase 1 Completed

78 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT02842580 2024-07-10

HIGH-LIGHT

Phase 2 Terminated

21 enrolled 12 charts

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Phase 1 Terminated

2 enrolled

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT04694183 2024-02-07

The Conversion Therapy of Chemotherapy Plus Camrelizumab in Metastatic Gastric Cancer

37 enrolled

Neoplasm Metastasis, Stomach Neoplasms

NCT03698461 2024-01-31

CLIMB

20 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT04617457 2024-01-12

HOLIPANC

Phase 2 Unknown

150 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT05237349 2024-01-05

Envafolimab Combined With Chemotherapy in Metastatic or Recurrent Gastric Adenocarcinoma

Phase 2 Unknown

38 enrolled

Neoplasm Metastasis

NCT03783936 2023-12-19

Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas

18 enrolled 16 charts

Adenocarcinoma Of Esophagus, Neoplasm Metastasis

NCT01718873 2023-04-12

OBELICS

Phase 3 Completed

230 enrolled 12 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT03487016 2022-09-08

FOOTPATH

Phase 2 Unknown

270 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT02080221 2022-08-01

BrUOG 292: FOLFOX-A For Metastatic Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial

50 enrolled 10 charts

Neoplasm Metastasis, Pancreatic Neoplasms

NCT02625610 2022-06-09

Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)

Phase 3 Completed

499 enrolled 22 charts

Neoplasm Metastasis, Neoplasms

NCT02384850 2022-04-08

SENTINEL

Phase 1 Terminated

10 enrolled 13 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT00321100 2022-01-12

Combination of Cetuximab, Capecitabine, and Oxaliplatin With or Without Bevacizumab

Phase 2 Terminated

23 enrolled 8 charts

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT01442649 2022-01-11

Efficacy of Chemotherapy, Associated to Either Cetuximab or Bevacizumab, in KRAS Wild-type Metastatic Colorectal Cancer Patients With Progressive Disease After Receiving First-line Treatment With Bevacizumab

133 enrolled

Adenocarcinoma, Neoplasm Metastasis, Colorectal Neoplasms

NCT00297596 2021-10-28

Trastuzumab and Oxaliplatin in Patients With Metastatic Breast Cancer

25 enrolled 6 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT00591123 2021-10-01

Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia

38 enrolled 14 charts

Adenocarcinoma Of Esophagus, Neoplasm Metastasis

NCT01276379 2021-07-02

POSIBA

221 enrolled 17 charts

Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies, Colorectal Neoplasms

NCT02128243 2021-03-26

MATEO

242 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Neoplasm Metastasis, Stomach Neoplasms

NCT00006050 2021-02-17

Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT01652976 2021-01-05

FOLFOX-D

44 enrolled 18 charts

Adenocarcinoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT00212615 2020-11-06

XELOX III. Xeloda in Combination With Eloxatin for Patients With Advanced or Metastatic Colorectal Cancer

Phase 2/3 Completed

116 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT01858649 2020-10-22

BEV-ONCO2012

60 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT01387373 2020-10-05

Intra-hepatic Chemotherapy in Patient With Non-resectable Liver Metastases From Breast Cancer