NCT04784715 2026-02-20Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)AstraZenecaPhase 3 Active not recruiting1,157 enrolled 3 FDA
NCT06174987 2025-10-15A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)Daiichi SankyoPhase 3 Recruiting50 enrolled
NCT03734029 2025-10-06Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04]Daiichi SankyoPhase 3 Active not recruiting557 enrolled 22 charts 2 FDA
NCT04014075 2025-04-03DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)Daiichi SankyoPhase 2 Completed79 enrolled 19 charts
NCT03523572 2025-01-27Trastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial CancerDaiichi SankyoPhase 1 Completed86 enrolled 22 charts
NCT05824975 2024-11-25A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)GI Innovation, Inc.Phase 1/2 Recruiting358 enrolled
NCT03383692 2023-12-11Study of DS-8201a for Participants With Advanced Solid Malignant TumorsDaiichi SankyoPhase 1 Completed40 enrolled 20 charts