Clinical Trials

20 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT05853575 2026-03-27

Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)

200 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT04639219 2026-03-23

DPT01

102 enrolled 18 charts

Neoplasm Metastasis

NCT06769698 2026-03-23

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

120 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT05755113 2026-03-12

A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma

40 enrolled

Sarcoma

Neoplasm Metastasis, Sarcoma

NCT04829604 2026-03-09

ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)

72 enrolled

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT07450859 2026-03-05

A Study of BT5528 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

39 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT04606771 2026-02-27

CoC

30 enrolled 20 charts

Carcinoma, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT07432295 2026-02-25

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

180 enrolled

Adenocarcinoma Of Esophagus, Neoplasm Metastasis, Stomach Neoplasms

NCT06005974 2026-02-23

A Study of REC-4881 in Participants With Cancers Which Have an AXIN1 or APC Mutation

18 enrolled

Neoplasm Metastasis

NCT06682806 2026-02-02

A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

6 enrolled

Esophageal Neoplasms, Neoplasm Metastasis

NCT03964727 2026-01-30

TROPiCS-03

223 enrolled 31 charts

Neoplasm Metastasis

NCT03697304 2026-01-27

Platform Trial Evaluating Safety and Efficacy of Ezabenlimab Anti- PD-1 Based Combination Therapies in PD-(L)1 naïve and PD- (L)1 Pretreated Patient Populations With Advanced/Metastatic Solid Tumours

211 enrolled 23 charts

Neoplasm Metastasis

NCT06792695 2026-01-20

CANTOR

120 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT06478862 2026-01-09

Promitil Treatment of Patients With Solid Tumors Associated With Deleterious Mutations Who Have Progressed After Therapy

19 enrolled

Neoplasm Metastasis, Ovarian Neoplasms

NCT00781612 2025-12-24

A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies

720 enrolled

Neoplasm Metastasis

NCT06824064 2025-12-23

VISTA-1

150 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT04463771 2025-12-10

POD1UM-204

206 enrolled

Neoplasm Metastasis, Endometrial Neoplasms

NCT04916002 2025-12-05

A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer

BreastDermatologicHead & NeckThoracic

77 enrolled 18 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Carcinoma, Merkel Cell, Triple Negative Breast Neoplasms

NCT04214288 2025-11-20

SERENA-2

240 enrolled 16 charts

Neoplasm Metastasis

NCT06246110 2025-11-12

A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC

70 enrolled

Neoplasm Metastasis

NCT05798611 2025-11-06

ARTIST

36 enrolled

Neoplasm Metastasis, Endometrial Neoplasms

NCT03539536 2025-11-05

Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer

270 enrolled 3 FDA

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms

NCT04003610 2025-11-04

Pemigatinib + Pembrolizumab vs Pemigatinib Alone vs Standard of Care for Urothelial Carcinoma (FIGHT-205)

7 enrolled 10 charts

Genitourinary

Acrocephalosyndactylia, Carcinoma, Transitional Cell, Neoplasm Metastasis

NCT04220866 2025-10-29

MK-1454-002

18 enrolled 14 charts

Head & Neck

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT05169437 2025-10-29

PAVO

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

22 enrolled 17 charts

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Urologic Neoplasms, Endometrial Neoplasms

NCT06558799 2025-10-28

LUNAR-4

69 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT04189445 2025-10-08

Futibatinib in Patients With Specific FGFR Aberrations

115 enrolled 19 charts

Neoplasm Metastasis, Stomach Neoplasms

NCT05271604 2025-09-26

A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Phase 2 Not yet recruiting

42 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasm Metastasis, Neoplasms

NCT06987058 2025-09-24

ROVER-01

10 enrolled

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Neoplasm Metastasis, Recurrence, Leukemia, Myeloid, Acute

NCT06397313 2025-09-23

POTAMI-61

230 enrolled

Myeloid

Neoplasm Metastasis, Primary Myelofibrosis

NCT05014815 2025-09-16

Ociperlimab With Tislelizumab and Chemotherapy in Participants With Untreated Metastatic Non-Small Cell Lung Cancer

272 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT06175221 2025-09-15

Autologous TLPO Vaccine Basket

63 enrolled

Neoplasm Metastasis, Neoplasms

NCT04646005 2025-09-08

Cemiplimab and ISA101b Vaccine in Adult Participants With Recurrent/Metastatic Human Papillomavirus (HPV)16 Cervical Cancer Who Have Experienced Disease Progression After First Line Chemotherapy

113 enrolled 18 charts

Adenocarcinoma, Uterine Cervical Neoplasms, Neoplasm Metastasis, Recurrence

NCT05374915 2025-08-28

Efficacy and Safety Study of REM-001 Photodynamic Therapy for Treatment of Cutaneous Metastatic Breast Cancer (CMBC)

15 enrolled

Neoplasm Metastasis

NCT02711553 2025-08-03

A Study of Ramucirumab (LY3009806) or Merestinib (LY2801653) in Advanced or Metastatic Biliary Tract Cancer

309 enrolled 22 charts

Biliary Tract Neoplasms, Neoplasm Metastasis

NCT03248492 2025-06-26

DESTINY-Breast01

253 enrolled 21 charts 2 FDA

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT05169684 2025-06-10

A Study of BMS-986218 or BMS-986218 Plus Nivolumab in Combination With Docetaxel in Participants With Metastatic Castration-resistant Prostate Cancer

10 enrolled 15 charts

Genitourinary

Neoplasm Metastasis, Prostatic Neoplasms, Castration-Resistant

NCT03505710 2025-05-30

DESTINY-Lung01

181 enrolled 17 charts 2 FDA

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT02380443 2025-05-16

AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer

13 enrolled 8 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT01864538 2025-05-11

A Phase 2 Biomarker - Enriched Study of TH-302 in Subjects With Advanced Melanoma

11 enrolled 8 charts

Dermatologic

Melanoma, Neoplasm Metastasis

NCT05673811 2025-04-16

VIRAGE

112 enrolled

Neoplasm Metastasis, Neoplasms

NCT04014075 2025-04-03

DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)

79 enrolled 19 charts

Neoplasm Metastasis

NCT04383210 2025-04-03

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors