Clinical Trials Browser

Phase 2 × Completed × Neoplasm Metastasis × Clear all

NCT00814021 2026-04-15

Sunitinib in Treating Patients With Kidney Cancer That Has Spread to the Brain

Phase 2 Completed

CNSGenitourinary

Brain Neoplasms, Carcinoma, Renal Cell, Kidney Neoplasms, Neoplasm Metastasis

NCT02087423 2026-04-06

ATLANTIC

Phase 2 Completed

446 enrolled 23 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT02964078 2026-04-02

Interleukin-2 and Pembrolizumab for Metastatic Kidney Cancer

Phase 2 Completed

27 enrolled 10 charts

Kidney Diseases, Kidney Neoplasms, Neoplasm Metastasis

NCT05068752 2026-03-30

Phase II Trial of Vemurafenib and Sorafenib in Pancreatic Cancer

Phase 2 Completed

10 enrolled 15 charts

Gastrointestinal

Neoplasm Metastasis, Pancreatic Neoplasms

NCT06538623 2026-03-24

Oxaliplatin Combined With Irinotecan Liposome Injection II Through Hepatic Artery Infusion (HAIC) Followed by 5-FU/LV (HAIC) or Tegorgor Oral Combination Therapy for Hepatic Metastasis of Pancreatic Cancer

Phase 2 Completed

Gastrointestinal

Neoplasm Metastasis, Pancreatic Neoplasms

NCT01900743 2026-03-13

REGO-SARC

Phase 2 Completed

Neoplasm Metastasis, Sarcoma

NCT01560416 2026-03-03

Fulvestrant With or Without Ganetespib in HR+ Breast Cancer

Phase 2 Completed

50 enrolled 14 charts

Breast Neoplasms, Neoplasm Metastasis

NCT04233567 2026-02-24

Infigratinib for the Treatment of Advanced or Metastatic Solid Tumors in Patients With FGFR Gene Mutations

Phase 2 Completed

17 enrolled 12 charts

Gastrointestinal

Neoplasm Metastasis, Cholangiocarcinoma

NCT01659151 2026-02-20

Vemurafenib With Lymphodepletion Plus Adoptive Cell Transfer & High Dose IL-2 Metastatic Melanoma

Phase 2 Completed

17 enrolled 11 charts

Melanoma, Neoplasm Metastasis

NCT03388190 2026-02-13

METIMMOX

Phase 2 Completed

80 enrolled 13 charts

Neoplasm Metastasis, Neoplasms

NCT03993353 2026-02-12

Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer

Phase 2 Completed

7 enrolled 14 charts

GastrointestinalHead & Neck

Pyridoxine-dependent epilepsy, Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Esophageal Neoplasms, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms

NCT03082534 2026-01-28

Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasm Metastasis, Oropharyngeal Neoplasms, Recurrence

NCT03697304 2026-01-27

Platform Trial Evaluating Safety and Efficacy of Ezabenlimab Anti- PD-1 Based Combination Therapies in PD-(L)1 naïve and PD- (L)1 Pretreated Patient Populations With Advanced/Metastatic Solid Tumours

Phase 2 Completed

211 enrolled 23 charts

Neoplasm Metastasis

NCT04326257 2026-01-08

Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior Immunotherapy

Phase 2 Completed

20 enrolled 13 charts

Diabetes Mellitus, Insulin-Dependent, 12, Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT02314364 2025-12-16

A Trial of Integrating SBRT With Targeted Therapy in Stage IV Oncogene-driven NSCLC

Phase 2 Completed

27 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT01771458 2025-11-24

SHIVA

Phase 2 Completed

Neoplasm Metastasis

NCT05052723 2025-11-19

Cabozantinib and Pembrolizumab in Metastatic Pancreas

Phase 2 Completed

21 enrolled 12 charts

Gastrointestinal

Adenocarcinoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT04220866 2025-10-29

MK-1454-002

Phase 2 Completed

18 enrolled 14 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT03652493 2025-10-06

PRO-CARBO

Phase 2 Completed

Neoplasm Metastasis

NCT02843165 2025-09-30

Checkpoint Blockade Immunotherapy Combined With Stereotactic Body Radiation in Advanced Metastatic Disease

Phase 2 Completed

106 enrolled 15 charts

Neoplasm Metastasis

NCT05271604 2025-09-26

A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Phase 2 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasm Metastasis, Neoplasms

NCT05014815 2025-09-16

Ociperlimab With Tislelizumab and Chemotherapy in Participants With Untreated Metastatic Non-Small Cell Lung Cancer

Phase 2 Completed

272 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT03098836 2025-09-12

PANTHER

Phase 2 Completed

93 enrolled 17 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT04646005 2025-09-08

Cemiplimab and ISA101b Vaccine in Adult Participants With Recurrent/Metastatic Human Papillomavirus (HPV)16 Cervical Cancer Who Have Experienced Disease Progression After First Line Chemotherapy

Phase 2 Completed

113 enrolled 18 charts

Adenocarcinoma, Uterine Cervical Neoplasms, Neoplasm Metastasis, Recurrence

NCT00712712 2025-08-29

MEDOR

Phase 2 Completed

78 enrolled 28 charts

Neoplasm Metastasis, Pain

NCT01979393 2025-08-01

IRCI Gynae Sarcomas, High Grade Uterine Sarcoma

Phase 2 Completed

Neoplasm Metastasis

NCT04300790 2025-07-29

METALLICA

Phase 2 Completed

BreastEndocrine

Breast Neoplasms, Hyperglycemia, Neoplasm Metastasis, Multiple Endocrine Neoplasia Type 1

NCT04420598 2025-06-24

DEBBRAH

Phase 2 Completed

41 enrolled 32 charts

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Meningeal Carcinomatosis

NCT02705820 2025-06-17

SWIPE

Phase 2 Completed

48 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT02061085 2025-06-08

MERIBEL

Phase 2 Completed

53 enrolled 11 charts

Breast Neoplasms, Ketosis, Neoplasm Metastasis

NCT03639935 2025-06-03

Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy

Phase 2 Completed

32 enrolled 14 charts

Gastrointestinal

Biliary Tract Neoplasms, Neoplasm Metastasis

NCT06312670 2025-05-29

Combining EPI-7386 With Enzalutamide and Androgen Deprivation Therapy for Metastatic Hormone-Sensitive Prostate Cancer

Phase 2 Completed

Neoplasm Metastasis, Prostatic Neoplasms

NCT03108131 2025-05-28

Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors

Phase 2 Completed

49 enrolled 10 charts

Adenocarcinoma, Mucinous, Neoplasm Metastasis, Neoplasms

NCT03250273 2025-05-28

A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinoma

Phase 2 Completed

44 enrolled 19 charts

Gastrointestinal

Neoplasm Metastasis, Pancreatic Neoplasms, Cholangiocarcinoma

NCT01441947 2025-05-25

Cabozantinib in Women With Metastatic Hormone-Receptor-Positive Breast Cancer

Phase 2 Completed

68 enrolled 11 charts

Breast Neoplasms, Neoplasm Metastasis

NCT03898908 2025-05-21

EBRAIN-MEL

Phase 2 Completed

48 enrolled 24 charts

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT02380443 2025-05-16

AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer

Phase 2 Completed

13 enrolled 8 charts

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT03570619 2025-05-08

IMPACT

Phase 2 Completed

56 enrolled 18 charts

Neoplasm Metastasis

NCT04602078 2025-04-24

AUREA

Phase 2 Completed

82 enrolled 20 charts

Carcinoma, Transitional Cell, Neoplasm Metastasis, Neoplasms

NCT05673811 2025-04-16

VIRAGE

Phase 2 Completed

Neoplasm Metastasis, Neoplasms

NCT04014075 2025-04-03

DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)

Phase 2 Completed

79 enrolled 19 charts

Neoplasm Metastasis

NCT03655886 2025-03-21

LoMP II

Phase 2 Completed

Neoplasm Metastasis, Prostatic Neoplasms

NCT06083662 2025-03-18

Neratinib and Trastuzumab Biosimilar in Patients with HER2 Mutated Advanced Solid Cancers

Phase 2 Completed

Neoplasm Metastasis

NCT02423603 2025-03-10

PAKT

Phase 2 Completed

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT04880863 2025-03-03

NT-NAP-102-1

Phase 2 Completed

38 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT04870177 2025-02-28

Study of AK112 in the Treatment of Advanced Gynecological Tumors

Phase 2 Completed

Uterine Cervical Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Endometrial Neoplasms

NCT01009177 2025-02-03

Effect of Bosentan in Patients With Metastatic Melanoma Treated With Dacarbazine (DTIC)

Phase 2 Completed

Melanoma, Neoplasm Metastasis

NCT04187833 2025-01-14

Nivolumab in Combination With Talazoparib in Melanoma and Mutations in BRCA or BRCA-ness Genes

Phase 2 Completed

8 enrolled 12 charts

Neoplasm Metastasis

NCT01884961 2025-01-13

IL2HD

Phase 2 Completed

DermatologicGenitourinary

Carcinoma, Renal Cell, Melanoma, Neoplasm Metastasis

NCT04551521 2025-01-08

CRAFT: The NCT-PMO-1602 Phase II Trial

Phase 2 Completed

Neoplasm Metastasis