Clinical Trials

13 enrolled

Neoplasm Metastasis

NCT05564377 2026-04-16

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

2,900 enrolled

Gynecologic

Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Endometrial Neoplasms

NCT05638295 2026-04-16

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

105 enrolled

Neoplasm Metastasis

NCT03682289 2026-04-15

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

GastrointestinalGenitourinaryGynecologic

89 enrolled

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Neoplasm Metastasis, Pancreatic Neoplasms, Endometrial Neoplasms

NCT03841617 2026-04-14

The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

Neoplasm Metastasis, Thyroid Neoplasms

NCT04927416 2026-04-14

The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer

54 enrolled

Neoplasm Metastasis, Thyroid Neoplasms

NCT05327010 2026-04-14

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

88 enrolled

Neoplasm Metastasis

NCT05821556 2026-04-14

Valproic Acid/Simvastatin Plus Gemcitabine/Nab-paclitaxel Based Regimens in Untreated Metastatic Pancreatic Adenocarcinoma Patients

240 enrolled

Neoplasm Metastasis

NCT03907475 2026-04-13

Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial

115 enrolled

Neoplasm Metastasis

NCT04550494 2026-04-13

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

BreastGastrointestinalGenitourinaryGynecologic

36 enrolled

Breast Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms

NCT05222620 2026-04-13

SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial

90 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT06067503 2026-04-13

Biomarkers to Detect Endocrine Therapy Resistance

8 enrolled

Breast Neoplasms, Neoplastic Cells, Circulating, Neoplasm Metastasis, Carcinoma, Lobular

NCT06311214 2026-04-13

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

500 enrolled

Neoplasm Metastasis

NCT07007559 2026-04-13

ASPEN-09-03

120 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT07423078 2026-04-13

WOLF

87 enrolled

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT06790602 2026-04-09

SWITCH

43 enrolled

Neoplasm Metastasis

NCT07042685 2026-04-09

Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer

50 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT06634875 2026-03-31

Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)

20 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT07312292 2026-03-30

RADIANT

15 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis

NCT07483983 2026-03-27

UNLOCK ASP3082

60 enrolled

Neoplasm Metastasis

NCT02133196 2026-03-24

T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer

85 enrolled

Thoracic

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Neoplasm Metastasis, Carcinoma, Adenosquamous

NCT07336238 2026-03-24

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

18 enrolled

Anxiety Disorders, Depression, Neoplasm Metastasis

NCT06769698 2026-03-23

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

120 enrolled

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT07477457 2026-03-17

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

45 enrolled

Neoplasm Metastasis, Osteosarcoma

NCT05755113 2026-03-12

A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma

40 enrolled

Neoplasm Metastasis, Sarcoma

NCT05607108 2026-03-11

A Study of ZEN003694 in People With Squamous Cell Lung Cancer

13 enrolled

Neoplasm Metastasis, Recurrence

NCT07057596 2026-03-06

NEO-TB

19 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis

NCT07450859 2026-03-05

A Study of BT5528 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

39 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT04771520 2026-03-02

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

DermatologicGastrointestinalSarcomaThoracic

50 enrolled

Lung Neoplasms, Melanoma, Neoplasm Metastasis, Sarcoma, Colorectal Neoplasms

NCT05686226 2026-02-27

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

GastrointestinalGenitourinaryGynecologicHead & Neck

20 enrolled

Anus Neoplasms, Uterine Cervical Neoplasms, Neoplasm Metastasis, Oropharyngeal Neoplasms, Penile Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms

NCT07282834 2026-02-27

Charlie-2

200 enrolled

Gynecologic

Neoplasm Metastasis, Neoplasms, Peritoneal Neoplasms

NCT07432295 2026-02-25

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

180 enrolled

Adenocarcinoma Of Esophagus, Neoplasm Metastasis, Stomach Neoplasms

NCT06630416 2026-02-24

Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

64 enrolled

Genitourinary

Urinary Bladder Neoplasms, Neoplasm Metastasis

NCT06058988 2026-02-23

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

CNS

Brain Neoplasms, Glioblastoma, Neoplasm Metastasis, Meningeal Carcinomatosis

NCT07193394 2026-02-23

H3RAKLES

20 enrolled

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT07407465 2026-02-17

CHIMERA

42 enrolled

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT06358677 2026-02-13

FACE

25 enrolled

Neoplasm Metastasis

NCT05726383 2026-02-10

Iscador® P (Mistletoe) Immunotherapy for Recurrent Osteogenic Sarcoma

32 enrolled

Bone Neoplasms, Neoplasm Metastasis, Sarcoma

NCT06778408 2026-02-05

HART

103 enrolled

Neoplasm Metastasis

NCT07176312 2026-02-04

ZANGEA

80 enrolled

Neoplasm Metastasis, Stomach Neoplasms

NCT07183319 2026-02-02

Circulating Tumor DNA Response In Urothelial Cancer

Genitourinary

Carcinoma, Transitional Cell, Neoplasm Metastasis

NCT05010031 2026-01-23

A Study of Reduced-dose Radiation in People With Metastatic Tumors With a Genetic Change

40 enrolled

Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies

NCT05419518 2026-01-23

Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metas

124 enrolled

Bone Neoplasms, Neoplasm Metastasis

NCT05502315 2026-01-23

CANOPY

47 enrolled

Neoplasm Metastasis

NCT05673928 2026-01-21

A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT05933395 2026-01-20

GERTRUDE

135 enrolled

Neoplasm Metastasis

NCT06792695 2026-01-20

CANTOR

120 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT05716516 2026-01-14

ESTHER

36 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT07079462 2025-12-24

Comparing 68Ga-FAPI PET-Guided Abdominal Radiotherapy Combined With Second-Line Standard Therapy and Cadonilimab Versus Second-Line Standard Therapy in Colorectal Cancer With Peritoneal Metastasis

40 enrolled

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT06824064 2025-12-23

VISTA-1

150 enrolled