Clinical Trials

36 enrolled

Gynecologic

Neoplasm Metastasis, Endometrial Neoplasms

NCT04003610 2025-11-04

Pemigatinib + Pembrolizumab vs Pemigatinib Alone vs Standard of Care for Urothelial Carcinoma (FIGHT-205)

7 enrolled 10 charts

Acrocephalosyndactylia, Carcinoma, Transitional Cell, Neoplasm Metastasis

NCT05169437 2025-10-29

PAVO

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

22 enrolled 17 charts

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Urologic Neoplasms, Endometrial Neoplasms

NCT04189445 2025-10-08

Futibatinib in Patients With Specific FGFR Aberrations

115 enrolled 19 charts

Neoplasm Metastasis, Stomach Neoplasms

NCT06175221 2025-09-15

Autologous TLPO Vaccine Basket

63 enrolled

Neoplasm Metastasis, Neoplasms

NCT05678257 2025-09-12

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

180 enrolled 16 charts

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT05691829 2025-07-29

IRRADIATE-Lung

19 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT03248492 2025-06-26

DESTINY-Breast01

253 enrolled 21 charts 1 FDA

Breast Neoplasms, Neoplasm Metastasis

NCT05169684 2025-06-10

A Study of BMS-986218 or BMS-986218 Plus Nivolumab in Combination With Docetaxel in Participants With Metastatic Castration-resistant Prostate Cancer

10 enrolled 15 charts

Neoplasm Metastasis, Prostatic Neoplasms, Castration-Resistant

NCT03505710 2025-05-30

DESTINY-Lung01

181 enrolled 17 charts 1 FDA

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT01864538 2025-05-11

A Phase 2 Biomarker - Enriched Study of TH-302 in Subjects With Advanced Melanoma

11 enrolled 8 charts

Dermatologic

Melanoma, Neoplasm Metastasis

NCT00640978 2025-05-01

Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer

16 enrolled 4 charts

Neoplasm Metastasis, Pancreatic Neoplasms

NCT04383210 2025-04-03

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

54 enrolled 11 charts

Fibromatosis, Gingival, 2, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Uterine Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT04629339 2025-03-13

Study of INCB086550 in Select Solid Tumors

DermatologicGastrointestinalGenitourinaryThoracic

16 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Melanoma, Neoplasm Metastasis

NCT05126433 2025-02-28

JAZZ EMERGE201

47 enrolled 16 charts

Neoplasm Metastasis

NCT04812535 2025-02-11

Non-comparative Study of IFX-1 Alone or IFX-1+Pembrolizumab in Patients With Locally Advanced or Metastatic cSCC.

30 enrolled 41 charts

Neoplasm Metastasis

NCT03991130 2025-02-06

High Dose IL-2 in Combination With Anti-PD-1 to Overcome Anti-PD-1 Resistance in Metastatic Melanoma and Renal Cell Carcinoma

DermatologicGenitourinary

6 enrolled

Carcinoma, Renal Cell, Melanoma, Neoplasm Metastasis

NCT03705403 2025-01-30

IMMUNOSABR2

88 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT04752358 2024-09-04

ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Esophageal or Esophagogastric Junction Cancers (SURPASS-2)

3 enrolled 15 charts

Esophageal Neoplasms, Neoplasm Metastasis

NCT04534283 2024-08-07

A Basket Trial of an ERK1/2 Inhibitor (LY3214996) in Combination With Abemaciclib.

16 enrolled 11 charts

Neoplasm Metastasis, Neoplasms

NCT04393454 2024-07-25

Study to Evaluate the Efficacy and Safety of Sirolimus in Subjects With Metastatic, Mismatch Repair Deficient Solid Tumors After Immunotherapy

6 enrolled 12 charts

Neoplasm Metastasis, Neoplasms

NCT02842580 2024-07-10

HIGH-LIGHT

21 enrolled 12 charts

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT03439085 2024-07-09

DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers

GastrointestinalGenitourinaryGynecologic

41 enrolled 13 charts

Anal Canal Carcinoma, Anus Neoplasms, Uterine Cervical Neoplasms, Neoplasm Metastasis, Neoplasms, Penile Neoplasms, Recurrence, Vaginal Neoplasms, Vulvar Neoplasms

NCT03562507 2024-05-20

ERICA

8 enrolled 11 charts

Carcinoma, Renal Cell, Neoplasm Metastasis

NCT04738292 2024-05-03

Onapristone and Fulvestrant for ER+ HER2- Metastatic Breast Cancer After Endocrine Therapy and CDK4/6 Inhibitors (The SMILE Study)

11 enrolled 10 charts

Neoplasm Metastasis

NCT01953926 2024-03-12

SUMMIT

582 enrolled 27 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms

NCT00019695 2024-03-04

Ketoconazole With or Without Alendronate Sodium in Treating Patients With Metastatic Prostate Cancer

Neoplasm Metastasis, Neoplasms, Prostatic Neoplasms, Genetic Diseases, Inborn

NCT01894633 2024-01-24

CLQ

73 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT04171700 2023-10-02

LODESTAR

BreastGastrointestinalGenitourinaryGynecologicSarcomaThoracic

83 enrolled 16 charts

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinosarcoma, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Leiomyosarcoma, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT02831933 2023-09-21

ENSIGN

11 enrolled 9 charts

DermatologicThoracic

Uveal Melanoma, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT00931606 2023-09-13

MK-7962-012

30 enrolled 32 charts

Classical hematology

Anemia, Neoplasm Metastasis, Neoplasms

NCT04720664 2023-08-28

OASIS

11 enrolled 10 charts

Breast Neoplasms, Neoplasm Metastasis

NCT02478320 2023-07-17

Phase II Study of Ilorasertib (ABT348) in Patients With CDKN2A Deficient Solid Tumors

12 enrolled 11 charts

Neoplasm Metastasis

NCT03740100 2023-07-14

HNSCC

8 enrolled 8 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis

NCT04863248 2023-04-14

PRESERVE 4

10 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT04069936 2022-08-02

Marrow Infiltrating Lymphocytes - Non-Small Cell Lung Cancer (MILs™ - NSCLC) Alone or in Combination With Nivolumab With or Without Tadalafil in Locally Advanced and Unresectable or Metastatic NSCLC

19 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT03147040 2022-07-19

GELATO

23 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT01759238 2022-07-01

OLGA

1 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT00810017 2022-05-19

Phase 2 Study of Trastuzumab and Etoposide for Her2 Positive Breast Cancer

2 enrolled 3 charts

Breast Neoplasms, Neoplasm Metastasis

NCT04003623 2022-05-10

Efficacy and Safety of Pemigatinib in Participants With Solid Tumors With FGFR Mutations or Translocations (FIGHT-208)

1 enrolled 2 charts

Neoplasm Metastasis

NCT03295552 2022-04-06

DETECT

12 enrolled

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT02978716 2022-03-23

Trilaciclib (G1T28), a CDK 4/6 Inhibitor, in Combination With Gemcitabine and Carboplatin in Metastatic Triple Negative Breast Cancer (mTNBC)

102 enrolled 51 charts