Clinical Trials Browser

Phase 2 × Interventional × Neoplasm Metastasis × Clear all

NCT05564377 2026-05-27

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Phase 2 Recruiting

Fallopian Tube Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Endometrial Neoplasms

NCT06311214 2026-05-27

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

Phase 2 Recruiting

Neoplasm Metastasis

NCT07608029 2026-05-27

Xiaochaihu Granules for Depression After Allogeneic Hematopoietic Stem Cell Transplantation

Phase 2 Not yet recruiting

Depressive Disorder, Neoplasm Metastasis

NCT07336238 2026-05-26

Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies

Phase 2 Recruiting

Anxiety Disorders, Depression, Neoplasm Metastasis

NCT04927416 2026-05-22

The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer

Phase 2 Recruiting

Neoplasm Metastasis, Thyroid Neoplasms

NCT05475171 2026-05-22

Triage of Advanced Cervical Cancer Through Immunotherapy Induction (TRACTION)

Phase 2 Suspended

Uterine Cervical Neoplasms, Neoplasm Metastasis

NCT05554380 2026-05-22

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Treatment Trial

Phase 2 Suspended

Neoplasm Metastasis

NCT05726383 2026-05-22

Iscador® P (Mistletoe) Immunotherapy for Recurrent Resectable Osteogenic Sarcoma

Phase 2 Recruiting

Bone Neoplasms, Neoplasm Metastasis, Sarcoma

NCT01885949 2026-05-20

Tivozanib + Enzalutamide in Adv Prostate Cancer

Phase 2 Terminated

5 enrolled 8 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT03841617 2026-05-20

The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

Phase 2 Recruiting

Neoplasm Metastasis, Thyroid Neoplasms

NCT07340619 2026-05-19

EPIBREAST

Phase 2 Not yet recruiting

Melanoma, Neoplasm Metastasis

NCT06824064 2026-05-18

VISTA-1

Phase 2 Recruiting

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT07594431 2026-05-18

Trial Comparing LATTICE Radiotherapy vs Moderately Dose-escalated Palliative Radiation for Patients With Metastases.

Phase 2 Not yet recruiting

Neoplasm Metastasis

NCT02710253 2026-05-15

Salvage Radiation Therapy in Treating Patients With Metastatic Cancer That Has Progressed After Systemic Immunotherapy

Phase 2 Active not recruiting

Other hematologic neoplasm

Neoplasm Metastasis, Hematologic Neoplasms

NCT05554341 2026-05-14

Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial

Phase 2 Active not recruiting

Neoplasm Metastasis

NCT07432295 2026-05-14

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

Phase 2 Recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Neoplasm Metastasis, Stomach Neoplasms

NCT02133196 2026-05-13

T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer

Phase 2 Recruiting

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Lung Neoplasms, Neoplasm Metastasis, Carcinoma, Adenosquamous

NCT03907475 2026-05-13

Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial

Phase 2 Recruiting

Neoplasm Metastasis

NCT04550494 2026-05-13

Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations

Phase 2 Recruiting

BreastGastrointestinalGenitourinaryGynecologic

Breast Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms

NCT05327010 2026-05-13

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

Phase 2 Recruiting

Neoplasm Metastasis

NCT05638295 2026-05-13

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

Phase 2 Active not recruiting

Neoplasm Metastasis

NCT06119217 2026-05-13

Phase 2 Study of TTX-030 and Chemotherapy With or Without Budigalimab for 1L mPDAC Patients

Phase 2 Completed

194 enrolled 16 charts

Gastrointestinal

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT07581821 2026-05-12

Sintilimab Combined With Anlotinib and Taxane-Based Chemotherap for Recurrent/Metastatic Nasopharyngeal Carcinoma

Phase 2 Recruiting

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

NCT05010031 2026-05-11

A Study of Reduced-dose Radiation in People With Metastatic Tumors With a Genetic Change

Phase 2 Recruiting

Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies

NCT06792695 2026-05-11

CANTOR

Phase 2 Recruiting

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT07576725 2026-05-08

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

Phase 2 Not yet recruiting

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidSarcomaThoracic

Clear-cell metastatic renal cell carcinoma, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Hodgkin Disease, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Sarcoma, Kaposi, Colorectal Neoplasms, Carcinoma, Merkel Cell

NCT06769698 2026-05-06

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Phase 2 Recruiting

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT03848286 2026-05-05

KL-A167 Injection in Recurrent or Metastatic Nasopharyngeal Carcinoma

Phase 2 Completed

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

NCT04807816 2026-05-05

TARSARC

Phase 2 Completed

Leiomyosarcoma, Neoplasm Metastasis, Sarcoma

NCT05716516 2026-05-05

ESTHER

Phase 2 Recruiting

Breast Neoplasms, Neoplasm Metastasis

NCT03872427 2026-05-04

Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN Study

Phase 2 Active not recruiting

54 enrolled 12 charts

Neoplasm Metastasis

NCT06416007 2026-05-04

Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors

Phase 2 Recruiting

Neoplasm Metastasis, Neoplasms

NCT07043608 2026-05-01

ZAMBONI

Phase 2 Not yet recruiting

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Neoplasm Metastasis

NCT07285993 2026-05-01

Detection and Outcomes in Metastatic Invasive Lobular Breast Cancer Through Novel F-18 FAP PET

Phase 2 Not yet recruiting

Breast Neoplasms, Neoplasm Metastasis

NCT07562581 2026-05-01

A Phase 2 Study of Luvometinib Combined With Anlotinib in KRAS-mutated NSCLC

Phase 2 Not yet recruiting

Neoplasm Metastasis

NCT04068649 2026-04-30

Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer

Phase 2 Recruiting

Neoplasm Metastasis

NCT03964727 2026-04-28

TROPiCS-03

Phase 2 Active not recruiting

227 enrolled 31 charts

Neoplasm Metastasis

NCT06846346 2026-04-28

GRACIE

Phase 2 Recruiting

Gastrointestinal

Adenocarcinoma Of Esophagus, Adenocarcinoma, Neoplasm Metastasis, Neoplasms

NCT07274774 2026-04-28

SBRT Plus Systemic Therapy vs Systemic Therapy Alone in BCLC C Hepatocellular Carcinoma

Phase 2 Recruiting

Gastrointestinal

Carcinoma, Hepatocellular, Neoplasm Metastasis

NCT03284385 2026-04-24

Testing AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2

Phase 2 Active not recruiting

Carcinoma, Renal Cell, Neoplasm Metastasis

NCT04116541 2026-04-24

MegaMOST

Phase 2 Recruiting

Neoplasm Metastasis

NCT05219435 2026-04-24

VEXILLUM

Phase 2 Completed

Neoplasm Metastasis

NCT06532539 2026-04-24

Cadonilimab With Chemoradiation for Recurrent and Oligometastatic Endometrial Carcinoma

Phase 2 Recruiting

Neoplasm Metastasis, Neoplasm Recurrence, Local, Neoplasms, Endometrial Neoplasms

NCT03682289 2026-04-23

Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors

Phase 2 Active not recruiting

GastrointestinalGenitourinaryGynecologic

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Neoplasm Metastasis, Pancreatic Neoplasms, Endometrial Neoplasms

NCT06475352 2026-04-23

FUDOSE

Phase 2 Recruiting

Gastrointestinal

Gastrointestinal Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Colorectal Neoplasms

NCT06027268 2026-04-22

ToPCourT

Phase 2 Active not recruiting

Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT07450859 2026-04-22

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

Phase 2 Recruiting

Gastrointestinal

Neoplasm Metastasis, Pancreatic Neoplasms

NCT04095208 2026-04-21

CONGRATS

Phase 2 Completed

Tertiary Lymphoid Structures, Neoplasm Metastasis, Neoplasms, Sarcoma

NCT07540650 2026-04-20

pRevenT

Phase 2 Not yet recruiting

Neoplasm Metastasis

NCT03909334 2026-04-17

Study of Osimertinib With and Without Ramucirumab in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis