Clinical Trials

23 enrolled 15 charts

BreastGenitourinary

Breast Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms, Triple Negative Breast Neoplasms

NCT02159989 2025-10-20

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

GastrointestinalGynecologic

83 enrolled 21 charts

Fibrolamellar hepatocellular carcinoma, Adenoma, Islet Cell, Neoplasm Metastasis, Ovarian Neoplasms

NCT00576654 2025-04-15

Veliparib and Irinotecan Hydrochloride in Treating Patients With Cancer That Is Metastatic or Cannot Be Removed by Surgery

73 enrolled

Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT02070549 2025-02-13

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

46 enrolled

Neoplasm Metastasis

NCT02503709 2025-02-10

Onalespib and CDKI AT7519 in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

29 enrolled

Neoplasm Metastasis

NCT01638533 2025-02-07

Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckLymphoidNETOther hematologic neoplasmSarcomaThoracic

37 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Glioma, Lung Neoplasms, Lymphoma, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Neuroendocrine Tumors, Hematologic Neoplasms

NCT04574583 2025-02-03

Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)

12 enrolled 17 charts

Neoplasm Metastasis

NCT01902173 2025-01-14

Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer

DermatologicOther hematologic neoplasm

27 enrolled 16 charts

Melanoma, Neoplasm Metastasis, Hematologic Neoplasms

NCT02143401 2024-11-22

Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors

29 enrolled

Fibrosis, Hepatitis B, Hepatitis C, Carcinoma, Hepatocellular, Neoplasm Metastasis, Neoplasms

NCT02595866 2024-08-09

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

DermatologicGastrointestinalLymphoidSarcomaThoracic

58 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Neoplasm Metastasis, Neoplasms, Recurrence, Sarcoma, Kaposi, HIV Infections

NCT00019578 2023-10-31

Stereotactic Radiosurgery in Treating Patients With Brain Tumors

CNS

Brain Neoplasms, Craniopharyngioma, Ependymoma, Glioma, Medulloblastoma, Meningioma, Neoplasm Metastasis, Neoplasms, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Genetic Diseases, Inborn

NCT00019760 2023-10-31

Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver

Colonic Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Neoplasm Metastasis, Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Genetic Diseases, Inborn

NCT02317874 2023-08-29

Testing the Addition of the Anti-Cancer Drug Talazoparib to the Combination of Carboplatin and Paclitaxel for the Treatment of Advanced Cancer

43 enrolled

Neoplasm Metastasis

NCT02898207 2023-04-26

Olaparib and Onalespib in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Recurrent Ovarian, Fallopian Tube, Primary Peritoneal, or Triple-Negative Breast Cancer

28 enrolled 21 charts

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT01822522 2023-01-10

Cabozantinib S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency Virus

36 enrolled 18 charts

Neoplasm Metastasis, HIV Infections

NCT03394027 2022-08-23

ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma

30 enrolled 15 charts

BreastGynecologic

Neoplasm Metastasis, Endometrial Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT00013871 2021-11-01

Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV Drugs

Phase NA Completed

300 enrolled

Hepatitis B, Measles, Neoplasm Metastasis, Pneumococcal Infections, Whooping Cough, HIV Infections

NCT01967823 2021-03-24

T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer

BreastCNSDermatologicGastrointestinalThoracic

11 enrolled 12 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Melanoma, Meningioma, Neoplasm Metastasis

NCT00339664 2020-03-30

Analyses of Human Samples Collected in Clinical Trials

GenitourinaryOther hematologic neoplasm

2,579 enrolled

Leukemia, Lymphoid, Leukemia, Myeloid, Neoplasm Metastasis, Prostatic Neoplasms

NCT01445418 2019-10-22

AZD2281 Plus Carboplatin to Treat Breast and Ovarian Cancer

103 enrolled

BreastGynecologic

Breast Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT00001507 2018-12-21

Chemotherapy and Progenitor Cell Transplantation to Treat Inflammatory Breast Cancer

107 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT02280811 2017-09-06

T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated Cancers

GastrointestinalGenitourinaryGynecologicHead & Neck

12 enrolled 19 charts

Anus Neoplasms, Uterine Cervical Neoplasms, Neoplasm Metastasis, Oropharyngeal Neoplasms, Penile Neoplasms, Vaginal Neoplasms

NCT00001328 2017-07-02

Gene Therapy for the Treatment of Brain Tumors

15 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis, Neoplasms, Multiple Acyl Coenzyme A Dehydrogenase Deficiency

NCT00028106 2017-07-02

131MIBG to Treat Malignant Pheochromocytoma

32 enrolled

Endocrine

Neoplasm Metastasis, Neoplasms, Pheochromocytoma

NCT00083733 2017-07-02

Genetic and Protein Profiling in Normal and Cancerous Breast Tissue

216 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00117013 2017-07-02

A Pilot Trial of Oral Topotecan for the Treatment of Refractory Advanced Solid Neoplasms Expressing HIF-1a

16 enrolled

Neoplasm Metastasis, Neoplasms

NCT00322140 2017-07-02

CDDO to Treat Solid Tumors and Lymphomas

7 enrolled

Lymphoid

Lymphoma, Neoplasm Metastasis

NCT00928382 2017-07-02

A Pilot Study to Explore Serum and Imaging Biomarkers in Patients With Spinal Cord Compression

30 enrolled

Neoplasm Metastasis, Neoplasms

NCT00453050 2015-05-06

Imiquimod and Laser Therapy With or Without a Green Dye in Treating Patients With Stage III or Stage IV Melanoma That Has Spread to Other Parts of the Skin

11 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis

NCT00021424 2015-04-30

Vaccine Therapy in Treating Patients With Stage IV Head and Neck Cancer

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasm Metastasis

NCT00030082 2015-04-30

Hepatic Arterial Infusion With Melphalan in Treating Patients With Unresectable Liver Cancer

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis

NCT00019825 2015-04-29

Decitabine in Treating Patients With Unresectable Lung or Esophageal Cancer or Malignant Mesothelioma of the Pleura

GastrointestinalOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pleural Effusion, Malignant, Small Cell Lung Carcinoma

NCT00020007 2015-04-29

Paclitaxel and Hyperthermic Perfusion in Treating Patients With Lung Cancer or Lung Metastases That Cannot Be Removed By Surgery

Thoracic

Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT00301730 2015-04-28

Cellular Adoptive Immunotherapy in Treating a Patient Who Has Undergone a Donor Stem Cell Transplant for Breast Cancer That Has Spread to the Lung

1 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT00390468 2014-05-28

Tandutinib in Treating Patients With Progressive Prostate Cancer and Bone Metastases

18 enrolled 5 charts

Neoplasm Metastasis, Pain, Prostatic Neoplasms

NCT00403065 2013-08-26

Dexamethasone and Supportive Care With or Without Whole-Brain Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer That Has Spread to the Brain and Cannot Be Removed By Surgery

Phase 3 Completed

1,000 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT01138358 2013-08-26

Study of Episodic Breathlessness in Patients With Lung Cancer or Other Advanced Disease

50 enrolled

OtherThoracic

Carcinoma, Non-Small-Cell Lung, Dyspnea, Lung Neoplasms, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT00554918 2013-08-07

Docetaxel and Prednisolone With or Without Zoledronic Acid and/or Strontium Chloride Sr 89 in Treating Patients With Prostate Cancer Metastatic to Bone That Has Not Responded to Hormone Therapy

300 enrolled

Neoplasm Metastasis, Prostatic Neoplasms

NCT00588913 2013-07-10

Adoptive Immunotherapy, Aldesleukin, and Zoledronate in Treating Patients With Stage IV Kidney Cancer and Lung Metastases

20 enrolled

Carcinoma, Renal Cell, Kidney Neoplasms, Neoplasm Metastasis

NCT00012155 2013-06-26

Gene Therapy in Treating Patients With Colon Cancer That Has Spread to the Liver

Colonic Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT00039572 2013-06-26

Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain

CNSDermatologicSarcoma

Brain Neoplasms, Glioblastoma, Melanoma, Neoplasm Metastasis, Central Nervous System Neoplasms, Gliosarcoma

NCT00082927 2013-06-26

Single-Dose Local Radiation Therapy Compared With Ibandronate in Treating Patients With Localized Metastatic Bone Pain

Phase 3 Completed

580 enrolled

Neoplasm Metastasis, Pain, Prostatic Neoplasms

NCT00003433 2013-06-21

Immunotherapy in Treating Patients With Resected Liver Metastases From Colon Cancer

Colonic Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT00003878 2013-06-21

Carmustine Implants in Treating Patients With Brain Metastases

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT00103298 2013-06-20

Isolated Hepatic Perfusion With Melphalan Followed by Combination Chemotherapy in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00301847 2013-02-11

Sorafenib in Treating Patients With Kidney Cancer That Has Spread to the Brain

44 enrolled

CNSGenitourinary

Brain Neoplasms, Carcinoma, Renal Cell, Kidney Neoplasms, Neoplasm Metastasis

NCT00001832 2012-12-21

Lymphocyte Re-infusion During Immune Suppression to Treat Metastatic Melanoma

170 enrolled 23 charts

BreastDermatologic

Breast Neoplasms, Melanoma, Neoplasm Metastasis

NCT00089401 2012-05-14

Isolated Hepatic Perfusion With Melphalan in Treating Patients With Unresectable Colorectal Cancer That Has Metastasized to the Liver

8 enrolled