Clinical Trials

Phase 1 Active not recruiting

Neoplasm Metastasis, Prostatic Neoplasms

NCT02321501 2026-05-20

Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer

37 enrolled

Phase 1 Active not recruiting

Neoplasm Metastasis

NCT04388852 2026-05-20

DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell Cancers

65 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Neoplasm Metastasis, Prostatic Neoplasms

NCT04588246 2026-05-20

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Phase 3 Terminated

19 enrolled 19 charts

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT07340619 2026-05-19

EPIBREAST

Phase 2 Not yet recruiting

51 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis

NCT07594626 2026-05-19

BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion

Phase 1/2 Not yet recruiting

72 enrolled

Phase 1 Active not recruiting

Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms

NCT05678010 2026-05-18

A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor Cancer

54 enrolled

Phase 2 Not yet recruiting

Neoplasm Metastasis

NCT07594431 2026-05-18

Trial Comparing LATTICE Radiotherapy vs Moderately Dose-escalated Palliative Radiation for Patients With Metastases.

80 enrolled

BreastCNSGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Neoplasm Metastasis

NCT01552434 2026-05-15

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

Phase 1 Terminated

154 enrolled

Breast Neoplasms, Carcinoma, Transitional Cell, Endocrine Gland Neoplasms, Castleman Disease, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms, Pharyngeal Neoplasms, Recurrence, Sarcoma, Soft Tissue Neoplasms, Thyroid Neoplasms, Urologic Neoplasms, Neurofibromatosis 2, Lymphangioleiomyomatosis, Neoplasms, Mesothelial, Erdheim-Chester Disease

NCT02710253 2026-05-15

Salvage Radiation Therapy in Treating Patients With Metastatic Cancer That Has Progressed After Systemic Immunotherapy

Phase 2 Active not recruiting

230 enrolled

Other hematologic neoplasm

Neoplasm Metastasis, Hematologic Neoplasms

NCT03911388 2026-05-15

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

24 enrolled

CNSSarcoma

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT04776837 2026-05-15

Predicting Disease Progression and/or Recurrence in Cancer

Completed

159 enrolled

Biliary Tract Neoplasms, Esophageal Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms, Disease Progression

NCT06302621 2026-05-15

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

70 enrolled

Neoplasm Metastasis, Cholangiocarcinoma

NCT03644303 2026-05-14

TRAP

Phase NA Completed

86 enrolled 27 charts

Phase EARLY_PHASE1 Completed

Neoplasm Metastasis, Prostatic Neoplasms

NCT04895592 2026-05-14

Radiosurgery Before Surgery for the Treatment of Brain Metastases

26 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis

NCT07587216 2026-05-14

Prospective Clinical Database Construction for Liver Cancer Diagnosis and Treatment

800 enrolled

Liver Neoplasms, Neoplasm Metastasis

NCT03086096 2026-05-13

CIREL

Completed

152 enrolled

Neoplasm Metastasis, Colorectal Neoplasms

NCT03775980 2026-05-13

CIEMAR

Completed

500 enrolled

Phase 1 Not yet recruiting

Colonic Neoplasms, Neoplasm Metastasis

NCT06663787 2026-05-13

HER2 CR

Active not recruiting

50 enrolled

Breast

Breast Neoplasms, Neoplasm Metastasis, Neoplasm, Residual

NCT07583654 2026-05-13

Safety, Tolerability, and Preliminary Antitumor Activity of Cationic Peptide-IL22BP mRNA in Advanced Solid Tumors

18 enrolled

Phase 1 Not yet recruiting

Neoplasm Metastasis

NCT07583914 2026-05-13

Safety, Tolerability, and Preliminary Antitumor Activity of Non-Cationic Peptide-CD47 siRNA in Advanced Solid Tumors

9 enrolled

Head & Neck

Head and Neck Neoplasms, Neoplasm Metastasis

NCT07584499 2026-05-13

MRG003

CNSGenitourinaryHead & NeckSarcoma

51 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Rhabdomyosarcoma, Rhabdoid Tumor

NCT05096923 2026-05-12

UNC-CAYACC

500 enrolled

Neoplasm Metastasis, Neoplasms

NCT06963723 2026-05-12

PROOF

Phase NA Recruiting

1,000 enrolled

Financial Stress, Neoplasm Metastasis

NCT07458347 2026-05-12

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

GastrointestinalGynecologicThoracic

145 enrolled

Biliary Tract Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07581821 2026-05-12

Sintilimab Combined With Anlotinib and Taxane-Based Chemotherap for Recurrent/Metastatic Nasopharyngeal Carcinoma

Phase 2 Recruiting

33 enrolled

Head & Neck

Nasopharyngeal Carcinoma, Neoplasm Metastasis, Recurrence

NCT05010031 2026-05-11

A Study of Reduced-dose Radiation in People With Metastatic Tumors With a Genetic Change

Phase 2 Recruiting

45 enrolled

Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies

NCT05100342 2026-05-08

Prospective Validation of a Points Score System Predicting 30-day Survival

214 enrolled

Phase EARLY_PHASE1 Recruiting

Neoplasm Metastasis

NCT06828588 2026-05-08

Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy

30 enrolled

BreastGastrointestinal

Esophageal Squamous Cell Carcinoma, Breast Neoplasms, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms

NCT07576725 2026-05-08

Low Dose, Reduced Frequency Nivolumab for the Treatment of Unresectable or Metastatic Cancer, AFFORD IO Trial

Phase 2 Not yet recruiting

50 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidSarcomaThoracic

Clear-cell metastatic renal cell carcinoma, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Hodgkin Disease, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Sarcoma, Kaposi, Colorectal Neoplasms, Carcinoma, Merkel Cell

NCT07572760 2026-05-07

Low to Moderate Load Power Training for Men With Metastatic Prostate Cancer.

Phase NA Recruiting

66 enrolled

Urogenital Diseases, Genital Diseases, Psychological Well-Being, Genital Neoplasms, Male, Motor Activity, Neoplasm Metastasis, Neoplasms, Prostatic Neoplasms, Urogenital Neoplasms

NCT06306924 2026-05-06

UNC Metastatic Cancer Radiation Therapy Registry

2,000 enrolled

Phase 1/2 Active not recruiting

Neoplasm Metastasis, Neoplasms

NCT03217747 2026-05-05

Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies

173 enrolled 28 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT03543696 2026-05-05

OLIGO

Phase NA Completed

150 enrolled

Neoplasm Metastasis

NCT04807816 2026-05-05

TARSARC

Phase 2 Completed

58 enrolled

Sarcoma

Leiomyosarcoma, Neoplasm Metastasis, Sarcoma

NCT05716516 2026-05-05

ESTHER

Phase 2 Recruiting

36 enrolled

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT07197671 2026-05-05

Y-NM600 in Patients Receiving Anti-PD-1 or Anti-PD-L1 for Metastatic Cancer

60 enrolled

Phase 1/2 Not yet recruiting

Neoplasm Metastasis

NCT07509008 2026-05-05

Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum

10 enrolled