Clinical Trials

28 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis, Recurrence

NCT05036681 2026-03-27

A Phase II Study of Futibatinib and Pembrolizumab in Metastatic Microsatellite Stable Endometrial Carcinoma

9 enrolled 10 charts

Gynecologic

Neoplasm Metastasis, Endometrial Neoplasms

NCT04789668 2026-03-18

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

BreastCNSDermatologicOther hematologic neoplasmThoracic

8 enrolled 13 charts

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Hematologic Neoplasms, Triple Negative Breast Neoplasms

NCT01613482 2026-03-16

TSARINE

Phase 3 Terminated

13 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT02565433 2026-03-16

PRAMECE

Phase NA Terminated

52 enrolled

Brain Neoplasms, Neoplasm Metastasis

NCT03694015 2026-03-11

SUPR-3D: Simple Unplanned Palliative Radiotherapy Versus 3D Conformal Radiotherapy for Patients With Bone Metastases

Phase NA Terminated

160 enrolled

Neoplasm Metastasis, Neoplasms, Neoplastic Processes, Pathologic Processes

NCT04785287 2026-03-03

Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies

EndocrineGastrointestinalThoracic

13 enrolled

Adrenal Gland Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT01885949 2026-02-24

Tivozanib + Enzalutamide in Adv Prostate Cancer

5 enrolled 7 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT03436056 2026-01-29

PRIMING

2 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT06162351 2026-01-02

TOPOLOGY

14 enrolled

Neoplasm Metastasis, Neoplasms

NCT06337630 2026-01-02

POP-ART

10 enrolled

Neoplasm Metastasis

NCT03503097 2025-10-01

GENTleMEN

799 enrolled

Neoplasm Metastasis, Prostatic Neoplasms

NCT05678257 2025-09-12

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

180 enrolled 16 charts

Phase EARLY_PHASE1 Terminated

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT03579446 2025-08-03

Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer

43 enrolled

Other hematologic neoplasm

Neoplasm Metastasis, Hematologic Neoplasms

NCT05691829 2025-07-29

IRRADIATE-Lung

19 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT05714553 2025-07-18

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

19 enrolled

Squamous Cell Carcinoma of Head and Neck, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Esophageal Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT03991741 2025-07-03

Adoptive Cell Transfer of Autologous Tumor Infiltrating Lymphocytes and High-Dose Interleukin 2 in Select Solid Tumors

BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

3 enrolled 9 charts

DermatologicHead & Neck

Head and Neck Neoplasms, Melanoma, Neoplasm Metastasis

NCT04588246 2025-06-06

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Phase 3 Terminated

19 enrolled 19 charts

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT02419495 2025-06-04

Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies

BreastDermatologicGenitourinaryGynecologicThoracic

221 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Fallopian Tube Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT05471271 2025-05-31

IL-2 PET Imaging in Advanced Solid Tumours

Phase NA Terminated

1 enrolled

Neoplasm Metastasis

NCT00640978 2025-05-01

Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer

16 enrolled 4 charts

Neoplasm Metastasis, Pancreatic Neoplasms

NCT00253318 2025-04-27

RAD001 Plus Docetaxel in Patients With Metastatic Breast Cancer

15 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT01529593 2025-03-24

Temsirolimus in Combination With Metformin in Patients With Advanced Cancers

34 enrolled

Neoplasm Metastasis

NCT03024437 2025-03-20

Atezolizumab in Combination With Entinostat and Bevacizumab in Patients With Advanced Renal Cell Carcinoma

31 enrolled 19 charts

Kidney Neoplasms, Neoplasm Metastasis

NCT03747484 2025-03-06

Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer

7 enrolled 15 charts

Dermatologic

Neoplasm Metastasis, Carcinoma, Merkel Cell

NCT03013946 2025-02-14

PREPARE

Phase 3 Terminated

121 enrolled

Carcinoma, Renal Cell, Neoplasm Metastasis, Recurrence

NCT03941639 2025-02-13

Using Imaging Data and Genomic Data to Predict Metastasis of Breast Cancer After Treatment

95 enrolled

Breast Neoplasms, Neoplasm Metastasis

NCT03991130 2025-02-06

High Dose IL-2 in Combination With Anti-PD-1 to Overcome Anti-PD-1 Resistance in Metastatic Melanoma and Renal Cell Carcinoma

DermatologicGenitourinary

Carcinoma, Renal Cell, Melanoma, Neoplasm Metastasis

NCT03705403 2025-01-30

IMMUNOSABR2

88 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT04534283 2024-08-07

A Basket Trial of an ERK1/2 Inhibitor (LY3214996) in Combination With Abemaciclib.

16 enrolled 11 charts

Neoplasm Metastasis, Neoplasms

NCT04393454 2024-07-25

Study to Evaluate the Efficacy and Safety of Sirolimus in Subjects With Metastatic, Mismatch Repair Deficient Solid Tumors After Immunotherapy

6 enrolled 12 charts

Neoplasm Metastasis, Neoplasms

NCT04957602 2024-07-24

LUTON

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT02842580 2024-07-10

HIGH-LIGHT

21 enrolled 12 charts

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT03439085 2024-07-09

DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated Cancers

GastrointestinalGenitourinaryGynecologic

41 enrolled 13 charts

Anal Canal Carcinoma, Anus Neoplasms, Uterine Cervical Neoplasms, Neoplasm Metastasis, Neoplasms, Penile Neoplasms, Recurrence, Vaginal Neoplasms, Vulvar Neoplasms

NCT03562507 2024-05-20

ERICA

8 enrolled 11 charts

Carcinoma, Renal Cell, Neoplasm Metastasis

NCT04738292 2024-05-03

Onapristone and Fulvestrant for ER+ HER2- Metastatic Breast Cancer After Endocrine Therapy and CDK4/6 Inhibitors (The SMILE Study)

11 enrolled 10 charts

Neoplasm Metastasis

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

2 enrolled

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT03257722 2024-02-28

PIL

4 enrolled 5 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Recurrence

NCT05408871 2024-02-15

Non-invasive Measurement of PD-L1 Levels With Positron Emission Tomography (PET) in Head and Neck Malignancies and Intracranial Metastases

7 enrolled

Head & NeckThoracic

Head and Neck Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT01894633 2024-01-24

CLQ

73 enrolled

Brain Neoplasms, Neoplasm Metastasis

NCT01545141 2023-10-27

Chemokine-Modulatory Regimen for Recurrent Resectable Colorectal Cancer

15 enrolled 9 charts

Neoplasm Metastasis, Recurrence, Colorectal Neoplasms

NCT02831933 2023-09-21

ENSIGN

11 enrolled 9 charts

DermatologicThoracic

Uveal Melanoma, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT04720664 2023-08-28

OASIS

11 enrolled 10 charts

Breast Neoplasms, Neoplasm Metastasis

NCT02095353 2023-08-23

Comparison of Contrast Agents for MRI Perfusion Analysis in Brain Tumor Patients

Brain Neoplasms, Glioma, Neoplasm Metastasis, Central Nervous System Neoplasms

NCT04729725 2023-08-14

SAR439459 and Cemiplimab for the Treatment of Advanced or Unresectable Solid Tumors, Strategic Alliance, TACTIC TRIAL

3 enrolled

Phase EARLY_PHASE1 Terminated

Neoplasm Metastasis

NCT02774291 2023-08-04

Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes

3 enrolled 6 charts

Brain Neoplasms, Neoplasm Metastasis

NCT04639245 2023-08-03

Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer

BreastGenitourinaryThoracic

1 enrolled 6 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Lung Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT00820456 2023-08-01

Metastatic Colorectal Cancer: Treatment Response With Dynamic Contrast MRI

Liver Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT02478320 2023-07-17

Phase II Study of Ilorasertib (ABT348) in Patients With CDKN2A Deficient Solid Tumors

12 enrolled 11 charts