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Phase

Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 28Burkitt Lymphoma 24Multiple Myeloma 20Lymphoma, Large B-Cell, Diffuse 20Leukemia, Myeloid, Acute 16Lymphoma, Non-Hodgkin 14Myelodysplastic Syndromes 13Lymphoma 13Lymphoma, Follicular 11Lymphoma, B-Cell 11Recurrence 10Ovarian Neoplasms 10Triple Negative Breast Neoplasms 9Leukemia, Lymphocytic, Chronic, B-Cell 9Hodgkin Disease 9Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 8Lymphoma, Mantle-Cell 8Leukemia, Myelogenous, Chronic, BCR-ABL Positive 8Leukemia 8Breast Neoplasms 8Pancreatic Neoplasms 7Neoplasms 7Hematologic Neoplasms 7Sarcoma 6Osteosarcoma 6Colorectal Neoplasms 6Lymphoma, B-Cell, Marginal Zone 5Leukemia, Myelomonocytic, Chronic 5Leukemia, Biphenotypic, Acute 5Graft vs Host Disease 5

Interventions

repotrectinib 1fludarabine phosphate 1fludarabine 1Mesna 1Etoposide 1Cyclophosphamide 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Neoplasms, Germ Cell and Embryonal × Cyclophosphamide × 30 days × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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