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Phase

Phase 1 1

Status

Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Multiple Myeloma 2Glioma 2Brain Neoplasms 2Rhabdoid Tumor 1Pinealoma 1Neuroectodermal Tumors, Primitive 1Neoplasms, Germ Cell and Embryonal 1Medulloblastoma 1Lymphoma, T-Cell, Peripheral 1Lymphoma, Non-Hodgkin 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Extranodal NK-T-Cell 1Lymphoma, B-Cell 1Immunoblastic Lymphadenopathy 1Gliosarcoma 1Glioblastoma 1Ependymoma 1Enteropathy-Associated T-Cell Lymphoma 1Choroid Plexus Carcinoma 1Central Nervous System Neoplasms 1

Interventions

Paclitaxel 5Etoposide 4Oxaliplatin 3Ifosfamide 3Granulocyte Colony-Stimulating Factor 3Gemcitabine 3Cyclophosphamide 3Cisplatin 3Carboplatin 3ribociclib 2fludarabine 2etoposide phosphate 2Stem Cell Transplantation 2Sirolimus 2Melphalan 2Filgrastim 2Everolimus 2Busulfan 2130-nm albumin-bound paclitaxel 2trametinib 1tozuleristide 1sonidegib 1ripretinib 1pralsetinib 1pembrolizumab 1pegylated granulocyte colony-stimulating factor 1pegfilgrastim 1pazopanib 1olaparib 1interferon gamma-1b 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Neoplasms, Germ Cell and Embryonal × Automobiles × Clear all
NCT03638167 2025-12-17

EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors

Seattle Children's Hospital

Phase 1 Completed
11 enrolled
CNS

Choroid Plexus Carcinoma, Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

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