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Phase

Phase 1/2 1

Status

Unknown 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Oligodendroglioma 1Neuroectodermal Tumors, Primitive 1Neoplasms, Germ Cell and Embryonal 1Medulloblastoma 1Glioma 1Breast Neoplasms 1Astrocytoma 1

Interventions

Cyclophosphamide 2sodium thiosulfate 1repotrectinib 1pralsetinib 1lutetium Lu 177 dotatate 1fludarabine phosphate 1fludarabine 1bintrafusp alfa protein, human 1Thrombopoietin 1Plicamycin 1Melphalan 1Mannitol 1ICE protocol 5 1Etoposide 1Drug Therapy 1Cytosine Deaminase 1Carboplatin 1Bevacizumab 1Azacitidine 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Neoplasms, Germ Cell and Embryonal × Mannitol × Clear all
NCT00983398 2021-10-26

Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors

OHSU Knight Cancer Institute

Phase 1/2 Unknown
17 enrolled
CNS

Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Neuroectodermal Tumors, Primitive

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