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Phase

Phase 1/2 1

Status

Unknown 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Brain Neoplasms 3Supratentorial Neoplasms 2Oligodendroglioma 2Medulloblastoma 2Kidney Neoplasms 2Central Nervous System Neoplasms 2Astrocytoma 2Urinary Bladder Neoplasms 1Prostatic Neoplasms 1Postoperative Complications 1Optic Nerve Glioma 1Neuroectodermal Tumors, Primitive 1Neoplasms, Germ Cell and Embryonal 1Nasopharyngeal Carcinoma 1Intracranial Hypertension 1Hemorrhage 1Gliosarcoma 1Glioma 1Glioblastoma 1Familial ependymoma 1Drug-Related Side Effects and Adverse Reactions 1Carcinoma, Renal Cell 1Breast Neoplasms 1

Interventions

Etoposide 10Cisplatin 9Cyclophosphamide 7etoposide phosphate 5Paclitaxel 5Ifosfamide 5Granulocyte Colony-Stimulating Factor 5Carboplatin 5fludarabine 4Sirolimus 4Gemcitabine 4pembrolizumab 3fludarabine phosphate 3Sunitinib 3Mesna 3Melphalan 3Filgrastim 3Drug Therapy 3Brentuximab Vedotin 3Bleomycin 3Bevacizumab 3Automobiles 3tremelimumab 2sodium thiosulfate 2pegfilgrastim 2lutetium Lu 177 dotatate 2durvalumab 2Vorinostat 2Stem Cell Transplantation 2Oxaliplatin 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Neoplasms, Germ Cell and Embryonal × Mannitol × Clear all
NCT00983398 2021-10-26

Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors

OHSU Knight Cancer Institute

Phase 1/2 Unknown
17 enrolled
CNS

Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Neuroectodermal Tumors, Primitive

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