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Phase

Phase NA 1Phase 2 1Phase 1 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Genitourinary 1Gastrointestinal 1Dermatologic 1CNS 1

Conditions

Sarcoma 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Leukemia, Myeloid, Acute 5Osteosarcoma 4Melanoma 4Lymphoma 4Leukemia 4Wilms Tumor 3Neuroblastoma 3Hematologic Neoplasms 3Rhabdoid Tumor 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Neuroectodermal Tumors, Primitive, Peripheral 2Neoplasms 2Myelodysplastic Syndromes 2Kidney Neoplasms 2Hepatoblastoma 2Graft vs Host Disease 2Carcinoma, Renal Cell 2Carcinoma, Hepatocellular 2Burkitt Lymphoma 2Stomach Neoplasms 1Sarcoma, Ewing 1Sarcoma, Clear Cell 1Rhabdomyosarcoma 1Retinoblastoma 1Recurrence 1Rectal Neoplasms 1Primary Myelofibrosis 1Pancreatic Neoplasms 1

Interventions

Automobiles 3fludarabine 2Sirolimus 2Granulocyte Colony-Stimulating Factor 2Gemcitabine 2Cyclophosphamide 2trametinib 1sonidegib 1ripretinib 1ribociclib 1pembrolizumab 1pegylated granulocyte colony-stimulating factor 1keyhole-limpet hemocyanin 1interferon gamma-1b 1guadecitabine 1fludarabine phosphate 1Vorinostat 1Topotecan 1Tetrahydrouridine 1Tetanus Toxoid 1Stem Cell Transplantation 1Simvastatin 1Photochemotherapy 1Oncolytic Virotherapy 1Mesna 1Melphalan 1Interferon-gamma 1Immunotherapy 1Filgrastim 1Dihematoporphyrin Ether 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Neoplasms, Germ Cell and Embryonal × Mesna × Clear all
NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

St. Jude Children's Research Hospital

Phase 1 Recruiting
48 enrolled
CNSDermatologicGastrointestinalGenitourinarySarcoma

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

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