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Phase

Phase EARLY_PHASE1 1Phase 1/2 1

Status

Unknown 1Suspended 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 1CNS 1

Conditions

Mesothelioma, Malignant 5Hepatoblastoma 5Ototoxicity 4Medulloblastoma 4Central Nervous System Neoplasms 4Peritoneal Neoplasms 3Ovarian Neoplasms 3Hearing Loss 3Gastrointestinal Neoplasms 3Drug-Related Side Effects and Adverse Reactions 3Testicular Neoplasms 2Stomach Neoplasms 2Sarcoma 2Oligodendroglioma 2Neoplasms, Germ Cell and Embryonal 2Liver Neoplasms 2Glioma 2Brain Neoplasms 2Astrocytoma 2Adrenocortical Carcinoma 2Thrombocytopenia 1Teratoma 1Seminoma 1Rhabdomyosarcoma 1Rectal Neoplasms 1Pelvic Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Oropharyngeal Neoplasms 1Optic Nerve Glioma 1

Interventions

Cisplatin 13Etoposide 11Paclitaxel 8Cyclophosphamide 7Carboplatin 7Ifosfamide 6etoposide phosphate 5Granulocyte Colony-Stimulating Factor 5Gemcitabine 5pembrolizumab 4fludarabine 4Sirolimus 4Bleomycin 4fludarabine phosphate 3Sunitinib 3Oxaliplatin 3Mesna 3Melphalan 3Filgrastim 3Drug Therapy 3Brentuximab Vedotin 3Bevacizumab 3Automobiles 3130-nm albumin-bound paclitaxel 3tremelimumab 2sodium thiosulfate 2ribociclib 2pralsetinib 2pegfilgrastim 2lutetium Lu 177 dotatate 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Neoplasms, Germ Cell and Embryonal × sodium thiosulfate × Clear all
NCT05756660 2025-10-20

Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Children's Hospital Medical Center, Cincinnati

Phase EARLY_PHASE1 Suspended
33 enrolled
Gastrointestinal

Ototoxicity, Neoplasms, Germ Cell and Embryonal, Hepatoblastoma

NCT00983398 2021-10-26

Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors

OHSU Knight Cancer Institute

Phase 1/2 Unknown
17 enrolled
CNS

Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Neuroectodermal Tumors, Primitive

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