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Phase

Phase EARLY_PHASE1 1Phase 1/2 1

Status

Unknown 1Suspended 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 1CNS 1

Conditions

Mesothelioma, Malignant 5Hepatoblastoma 3Drug-Related Side Effects and Adverse Reactions 3Central Nervous System Neoplasms 3Ototoxicity 2Oligodendroglioma 2Neoplasms, Germ Cell and Embryonal 2Medulloblastoma 2Glioma 2Gastrointestinal Neoplasms 2Astrocytoma 2Thrombocytopenia 1Testicular Neoplasms 1Stomach Neoplasms 1Seminoma 1Sarcoma 1Rhabdomyosarcoma 1Rectal Neoplasms 1Peritoneal Neoplasms 1Pelvic Neoplasms 1Ovarian Neoplasms 1Oropharyngeal Neoplasms 1Optic Nerve Glioma 1Neuroectodermal Tumors, Primitive 1Neoplasms 1Mouth Neoplasms 1Mesothelioma 1Lymphoma 1Liver Neoplasms 1Liposarcoma 1

Interventions

Etoposide 10Cisplatin 9Cyclophosphamide 7etoposide phosphate 5Paclitaxel 5Ifosfamide 5Granulocyte Colony-Stimulating Factor 5Carboplatin 5fludarabine 4Sirolimus 4Gemcitabine 4pembrolizumab 3fludarabine phosphate 3Sunitinib 3Mesna 3Melphalan 3Filgrastim 3Drug Therapy 3Brentuximab Vedotin 3Bleomycin 3Bevacizumab 3Automobiles 3tremelimumab 2sodium thiosulfate 2pegfilgrastim 2lutetium Lu 177 dotatate 2durvalumab 2Vorinostat 2Stem Cell Transplantation 2Oxaliplatin 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Neoplasms, Germ Cell and Embryonal × sodium thiosulfate × Clear all
NCT05756660 2025-10-20

Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Children's Hospital Medical Center, Cincinnati

Phase EARLY_PHASE1 Suspended
33 enrolled
Gastrointestinal

Ototoxicity, Neoplasms, Germ Cell and Embryonal, Hepatoblastoma

NCT00983398 2021-10-26

Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors

OHSU Knight Cancer Institute

Phase 1/2 Unknown
17 enrolled
CNS

Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Neuroectodermal Tumors, Primitive

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