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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Lymphoid 1CNS 1

Conditions

Carcinoma, Basal Cell 6Skin Neoplasms 3Prostatic Neoplasms 2Pancreatic Neoplasms 2Ovarian Neoplasms 2Neoplasms, Basal Cell 2Neoplasm Metastasis 2Multiple Myeloma 2Lung Neoplasms 2Carcinoma, Hepatocellular 2Carcinoma 2Basal Cell Nevus Syndrome 2Thrombocythemia, Essential 1Squamous Cell Carcinoma of Head and Neck 1Rhabdoid Tumor 1Recurrence 1Pyloric Stenosis, Hypertrophic 1Primary Myelofibrosis 1Polycythemia Vera 1Pinealoma 1Pancreatic Ductal Adenocarcinoma 1Pancreatic Diseases 1Oligodendroglioma 1Neuroectodermal Tumors, Primitive 1Neoplasms, Neuroepithelial 1Neoplasms, Germ Cell and Embryonal 1Neoplasms 1Myelodysplastic-Myeloproliferative Diseases 1Myelodysplastic Syndromes 1Microphthalmia, Isolated, with Coloboma 5 1

Interventions

Etoposide 10Cisplatin 9Cyclophosphamide 7etoposide phosphate 5Paclitaxel 5Ifosfamide 5Granulocyte Colony-Stimulating Factor 5Carboplatin 5fludarabine 4Sirolimus 4Gemcitabine 4pembrolizumab 3fludarabine phosphate 3Sunitinib 3Mesna 3Melphalan 3Filgrastim 3Drug Therapy 3Brentuximab Vedotin 3Bleomycin 3Bevacizumab 3Automobiles 3tremelimumab 2sodium thiosulfate 2pegfilgrastim 2lutetium Lu 177 dotatate 2durvalumab 2Vorinostat 2Stem Cell Transplantation 2Oxaliplatin 2

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Neoplasms, Germ Cell and Embryonal × sonidegib × Clear all
NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
68 enrolled
CNSLymphoid

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

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