Clinical Trials

100 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Lung Neoplasms, Neoplasms, Germ Cell and Embryonal, Neoplasms, Squamous Cell

NCT01890486 2026-04-13

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

LymphoidMyeloidOther hematologic neoplasmPlasma cell

2,000 enrolled

Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasms, Germ Cell and Embryonal, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03911388 2026-04-13

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

24 enrolled

CNSSarcoma

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT04185038 2026-04-13

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

90 enrolled

Choroid Plexus Carcinoma, Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT05278208 2026-04-13

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

65 enrolled

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Central Nervous System Neoplasms

NCT03067181 2026-04-07

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Phase 3 Recruiting

1,780 enrolled

Neoplasms, Germ Cell and Embryonal, Teratoma, Carcinoma, Embryonal, Endodermal Sinus Tumor

NCT03093116 2026-04-03

TRIDENT-1

EndocrineGastrointestinalHead & NeckNETSarcomaThoracic

500 enrolled 5 FDA

Adenocarcinoma, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Sarcoma, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Neuroectodermal Tumors, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT05092451 2026-03-18

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

LymphoidMyeloidOther hematologic neoplasmPlasma cell

80 enrolled

Hodgkin Disease, Leukemia, Plasma Cell, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasms, Germ Cell and Embryonal, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, B-Cell

NCT06276491 2026-03-17

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

282 enrolled

GenitourinaryGynecologic

Testicular Germ Cell Tumor, Neoplasms, Germ Cell and Embryonal, Ovarian Neoplasms, Testicular Neoplasms, Endometrial Neoplasms

NCT02099734 2026-02-04

Germ Cell Tumor and Testicular Tumor DNA Registry

1,000 enrolled

Genitourinary

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT06828185 2026-02-04

PRESERVE

80 enrolled

Genitourinary

Neoplasms, Germ Cell and Embryonal, Pain, Postoperative, Testicular Neoplasms

NCT06866964 2026-02-02

ASPIRE

Classical hematologyGenitourinary

35 enrolled

Neoplasms, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms, Venous Thromboembolism

NCT05259605 2025-12-17

Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification

1,650 enrolled

Ependymoma, Glioma, Hemangiopericytoma, Neoplasms, Germ Cell and Embryonal, Pinealoma, Choroid Plexus Neoplasms, Hemangioblastoma

NCT06937866 2025-11-21

Maintenance Zanzalintinib With Etoposide After HDCT in GCT

38 enrolled

Neoplasms, Germ Cell and Embryonal

NCT05293197 2025-11-20

SONOKID

24 enrolled

Brain Neoplasms, Glioma, Neoplasms, Germ Cell and Embryonal

NCT05564026 2025-10-24

Molecular Epidemiology of Pediatric Germ Cell Tumors

1,151 enrolled

Choriocarcinoma, Neoplasms, Germ Cell and Embryonal, Teratoma, Carcinoma, Embryonal, Germinoma, Endodermal Sinus Tumor

NCT07188441 2025-09-23

Treatment of Newly Diagnosed Central Malignant Germ Cell Tumor People With Teniposide Injection Combined With Cisplatin.

40 enrolled

Neoplasms, Germ Cell and Embryonal

NCT06133543 2025-09-15

RAISN

44 enrolled

Nonseminomatous germ cell tumor, Neoplasms, Germ Cell and Embryonal, Seminoma

NCT04099797 2025-09-04

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

37 enrolled

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Glioma, Neoplasms, Germ Cell and Embryonal, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT07121322 2025-08-13

DACT-GCT

33 enrolled

Neoplasms, Germ Cell and Embryonal

NCT06418789 2025-08-03

GERMAN

25 enrolled

Nonseminomatous germ cell tumor, Choriocarcinoma, Neoplasms, Germ Cell and Embryonal, Teratoma, Germinoma, Seminoma, Endodermal Sinus Tumor

NCT02582697 2025-06-15

P3BEP

Phase 3 Recruiting

500 enrolled

Neoplasms, Germ Cell and Embryonal

NCT05874063 2025-06-15

GIG-T

Phase 3 Recruiting

387 enrolled

Neoplasms, Germ Cell and Embryonal

NCT05711992 2025-05-08

Rare Embryonal Tumors of the Central Nervous System: International Registry

300 enrolled

Neoplasms, Germ Cell and Embryonal

NCT04804007 2025-04-18

Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT

64 enrolled

Nonseminomatous germ cell tumor, Neoplasms, Germ Cell and Embryonal

NCT05298995 2025-02-05

GD2-CAR T Cells for Pediatric Brain Tumours

54 enrolled

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Glioma, Medulloblastoma, Neoplasms, Germ Cell and Embryonal

NCT05889585 2024-10-18

HGT-QoL

180 enrolled

Neoplasms, Germ Cell and Embryonal

NCT06421805 2024-05-20

MTDPUMCH

2,000 enrolled

Lymphoid

Thymic epithelial tumor, Goiter, Substernal, Lymphoma, Mediastinal Cyst, Neoplasms, Germ Cell and Embryonal, Neurilemmoma, Teratoma

NCT05672043 2023-01-05

GRIPP

400 enrolled

Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Central Nervous System Neoplasms

NCT04949282 2022-12-23

SEPTRALU

EndocrineGastrointestinalNET

5,000 enrolled

Gastro-enteropancreatic neuroendocrine tumor, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Pancreatic Diseases, Pancreatic Neoplasms, Stomach Neoplasms, Neuroectodermal Tumors, Neuroendocrine Tumors

NCT05502224 2022-11-08

Multidisciplinary Approach to Fatigue