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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Leukemia, Myeloid, Acute 38Neoplasm Metastasis 37Multiple Myeloma 29Lymphoma 23Pancreatic Neoplasms 17Colorectal Neoplasms 17Breast Neoplasms 17Prostatic Neoplasms 16Myelodysplastic Syndromes 16Lung Neoplasms 15Leukemia, Lymphocytic, Chronic, B-Cell 15Burkitt Lymphoma 15Lymphoma, Large B-Cell, Diffuse 14Melanoma 13Triple Negative Breast Neoplasms 12Precursor Cell Lymphoblastic Leukemia-Lymphoma 12Ovarian Neoplasms 12Carcinoma, Non-Small-Cell Lung 12Sarcoma 9Neuroblastoma 9Neoplasms 9Glioma 9Carcinoma, Renal Cell 9Squamous Cell Carcinoma of Head and Neck 8Lymphoma, T-Cell 8Leukemia, Biphenotypic, Acute 8Fallopian Tube Neoplasms 8Endometrial Neoplasms 8Myeloproliferative Disorders 7Lymphoma, Non-Hodgkin 7

Interventions

Bevacizumab 3contrast agent BR1 2pralsetinib 1pembrolizumab 1Pemetrexed 1Paclitaxel 1Microbubbles 1Gemcitabine 1Cisplatin 1Carboplatin 1Biopsy 1130-nm albumin-bound paclitaxel 1

Date Range

30 days90 days1 yearAll

Options

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Clinical Trials

1 trials
RecentStart dateEnrollment
Neoplasms, Nerve Tissue × Biopsy × 90 days × Clear all
NCT07416188 2026-06-03

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
40 enrolled
CNS

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Nerve Tissue, Recurrence, Central Nervous System Neoplasms

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