Clinical Trials Browser

Adrenal Cortex Neoplasms, Carcinoma, Renal Cell, Neoplasm Metastasis, Neoplasms, Unknown Primary, Paraganglioma, Penile Neoplasms, Pheochromocytoma, Carcinoma, Small Cell, Vascular Neoplasms

NCT03752333 2026-01-22

CUPem

Phase 2 Completed

35 enrolled

Tumor-Agnostic

Neoplasms, Unknown Primary

NCT03498521 2025-11-19

CUPISCO

Phase 2 Completed

529 enrolled 16 charts

Tumor-Agnostic

Neoplasms, Unknown Primary

NCT04273061 2025-09-22

CAPTIV-8

Phase 2 Recruiting

200 enrolled

BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasms, Unknown Primary, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT03391973 2025-04-25

CUP

Phase 2 Active not recruiting

26 enrolled

Tumor-Agnostic

Neoplasms, Unknown Primary

NCT04802876 2025-03-21

ACROPOLI

Phase 2 Active not recruiting

184 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

Adenocarcinoma Of Esophagus, Adenocarcinoma of Lung, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Uveal Melanoma, Anus Neoplasms, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Neoplasms, Unknown Primary, Sarcoma, Thyroid Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02607202 2024-01-26

AGNOSTOS

Phase 2 Completed

57 enrolled

Tumor-Agnostic

Neoplasms, Unknown Primary

NCT01845337 2023-05-12

TOFFEE

Phase 2 Completed

59 enrolled

Gastrointestinal

Bile Duct Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms

NCT04276597 2023-03-10

PUTNET

Phase 2 Withdrawn

CNSDermatologicEndocrineNET

Neoplasms, Unknown Primary, Paraganglioma, Pheochromocytoma, Carcinoma, Merkel Cell, Neuroendocrine Tumors

NCT00003526 2020-12-17

Antineoplaston Therapy in Treating Patients With Cancer of Unknown Primary Origin

Phase 2 Terminated

8 enrolled 5 charts

Tumor-Agnostic

Neoplasms, Unknown Primary

NCT00357630 2020-11-02

Gemcitabine in Treating Patients With Metastatic Cancer of Unknown Primary

Phase 2 Completed

52 enrolled

Neoplasms, Unknown Primary, Pain

NCT04131621 2020-04-15

CheCUP

Phase 2 Unknown

194 enrolled

Tumor-Agnostic

Neoplasms, Unknown Primary

NCT02764216 2019-04-09

Elective Mucosal Irradiation in Head-and-Neck Cancer of Unknown Primary

Phase 2 Unknown

48 enrolled

Head & Neck

Head and Neck Neoplasms, Neoplasms, Unknown Primary

NCT00004005 2017-04-26

Irinotecan Followed By Fluorouracil and Leucovorin in Treating Patients With Stage III or Stage IV Colorectal Carcinoma (Cancer), Other Refractory Carcinoma, or Metastatic Adenoma (Cancer) of Unknown Primary Origin

Phase 2 Completed

12 enrolled

Gastrointestinal

Colonic Neoplasms, Neoplasms, Unknown Primary, Rectal Neoplasms, Colorectal Neoplasms

NCT00066781 2017-04-04

Gemcitabine and Irinotecan in Treating Patients With Cancer of Unknown Primary

Phase 2 Completed

31 enrolled 8 charts

Tumor-Agnostic

Neoplasms, Unknown Primary

NCT00936702 2017-03-21

Carboplatin, Paclitaxel, and Everolimus in Treating Patients With Previously Untreated Cancer of Unknown Primary

Phase 2 Completed

46 enrolled 13 charts

Tumor-Agnostic

Neoplasms, Unknown Primary

NCT00003657 2017-01-20

High-dose ICE With Amifostine

Phase 2 Completed

24 enrolled

CNSGenitourinaryGynecologicHead & NeckSarcomaThoracic

AIDS-related Kaposi sarcoma, Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Chondrosarcoma, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasms, Unknown Primary, Ovarian Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Testicular Neoplasms, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT02590055 2015-10-28