Clinical Trials

GastrointestinalGynecologicOther solid neoplasmThoracic

100 enrolled

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

NCT07127874 2026-06-05

A Study of PHN-012 in Patients With Advanced Solid Tumors

165 enrolled

GastrointestinalThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms

NCT07525141 2026-06-05

A Study of JNJ-1761981 in Participants With Solid Tumors

66 enrolled

Neoplasms

NCT07614022 2026-06-05

A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL)

LymphoidOther hematologic neoplasm

26 enrolled

Leukemia, Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04189614 2026-06-04

An Efficacy and Safety Study of Cofetuzumab Pelidotin in Participants With PTK7-Expressing, Recurrent Non-Small Cell Lung Cancer

Phase 1 Terminated

65 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT04458259 2026-06-04

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Phase 1 Terminated

88 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicThoracic

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma

NCT04777994 2026-06-04

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

GenitourinaryHead & NeckThoracic

248 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Neoplasms, Recurrence

NCT06253871 2026-06-04

A Phase 1/1b Study of IAM1363 in HER2 Cancers

BreastCNSGastrointestinalThoracic

383 enrolled

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Neoplasms, Stomach Neoplasms

NCT06756035 2026-06-04

CT-95 in Advanced Cancers Associated With Mesothelin Expression

GastrointestinalGynecologicOther solid neoplasmThoracic

70 enrolled

Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT06764771 2026-06-03

A Study of BMS-986488 as Monotherapy and Combination Therapy in Participants With Advanced Malignant Tumors

GastrointestinalGenitourinaryThoracic

437 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Neoplasms, Colorectal Neoplasms

NCT07038369 2026-06-03

A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations

BreastGenitourinaryGynecologic

134 enrolled

Breast Diseases, Breast Neoplasms, Uterine Cervical Neoplasms, Genital Neoplasms, Female, Neoplasms, Neoplasms by Site, Ovarian Neoplasms, Prostatic Neoplasms, Urogenital Neoplasms, Uterine Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT07247110 2026-06-03

A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)

250 enrolled

Neoplasms

NCT07197554 2026-06-02

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

GastrointestinalGynecologicSarcoma

171 enrolled

Biliary Tract Neoplasms, Carcinoma, Hepatocellular, Neoplasms, Sarcoma, Ewing, Endometrial Neoplasms

NCT02379416 2026-06-01

Combination Nilotinib and Paclitaxel in Adults With Relapsed Solid Tumors

47 enrolled

Neoplasms

NCT06360354 2026-06-01

MTAPESTRY 103

120 enrolled

Gastrointestinal

Neoplasms, Pancreatic Neoplasms

NCT00463814 2026-05-29

AZD6244 (ARRY-142886) Solid Oral Dosage Formulation in Participants With Advanced Solid Malignancies

58 enrolled

Neoplasms

NCT04401020 2026-05-29

First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL

47 enrolled

Neoplasms

NCT07321106 2026-05-29

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

80 enrolled

Gastrointestinal

Colonic Neoplasms, Neoplasms, Colorectal Neoplasms

NCT06333951 2026-05-28

Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).

49 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT07612176 2026-05-28

A Phase 1 Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors

155 enrolled

Neoplasm Metastasis, Neoplasms

NCT07612488 2026-05-28

A Study of CS231295 in Patients With Advanced Solid Tumors

42 enrolled

Neoplasms

NCT00600496 2026-05-27

A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)

BreastDermatologicGastrointestinalGenitourinaryThoracic

140 enrolled

Breast Neoplasms, Colonic Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms

NCT03611595 2026-05-27

Cabozantinib in Combination With 13-cis-Retinoic Acid in Children With Relapsed or Refractory Solid Tumors

15 enrolled

Neoplasms

NCT04958239 2026-05-27

A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer

151 enrolled

Neoplasms

NCT06880549 2026-05-27

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

42 enrolled

Dermatologic

Melanoma, Neoplasm Metastasis, Neoplasms, Recurrence

NCT07438782 2026-05-27

First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors

97 enrolled

Neoplasms

NCT06533059 2026-05-26

A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors

BreastGenitourinaryGynecologic

110 enrolled

Breast Neoplasms, Uterine Cervical Neoplasms, Genital Neoplasms, Female, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05277051 2026-05-22

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

152 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06431594 2026-05-22

BEHOLD-1

675 enrolled

Neoplasms

NCT06551142 2026-05-22

PanTumor-101

845 enrolled

Neoplasms

NCT07578571 2026-05-22

A Phase 1 Study of IM-1617 in Participants With Advanced Cancer

BreastGastrointestinalThoracic

175 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT07600749 2026-05-22

Clinical Study of MK-4884 in Participants With Advanced or Metastatic Solid Tumors (MK-4884-001)

120 enrolled

Neoplasms

NCT07603479 2026-05-22

A Phase I Study of JL19001 Injection Alone or in Combination With Standard Therapy in Patients With Advanced Solid Tumors or Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

14 enrolled

Lymphoid

Lymphoma, Non-Hodgkin, Neoplasms

NCT03530397 2026-05-19

A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors

400 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Neoplasms

NCT04130542 2026-05-19

Phase 1 Trial of LVGN6051 as Single Agent and in Combination With Keytruda (Pembrolizumab) in Advanced or Metastatic Malignancy

105 enrolled

Neoplasms

NCT04635995 2026-05-19

Phase 1 Trial of LVGN7409 (CD40 Agonist Antibody) as Single Agent and Combination Therapies in Advanced or Metastatic Malignancy

66 enrolled

Neoplasms

NCT07409246 2026-05-19

A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

127 enrolled

Plasma cell

Multiple Myeloma, Neoplasms

NCT06626230 2026-05-18

Safety of Anal Curcumin

48 enrolled

Neoplasms

NCT07094204 2026-05-18

A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

364 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT07224776 2026-05-18

Sparsentan for the Treatment of VEGF Signaling Pathway Inhibitor-Associated Proteinuria