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NCT01586624 2021-10-07

A Phase I Trial of Vandetanib (AZD6474) and Selumetinib (AZD6244) for Solid Tumours Including Non Small Cell Lung Cancer (VanSel-1)

Phase 1 Completed

61 enrolled 23 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT00923247 2018-11-29

A Targeted Phase I/II Trial of ZD6474 (Vandetanib; ZACTIMA) Plus the Proteasome Inhibitor, Bortezomib (Velcade ), in Adults With Solid Tumors With a Focus on Hereditary or Sporadic, Locally Advanced or Metastatic Medullary Thyroid Cancer (MTC)

Phase 1/2 Terminated

22 enrolled 21 charts

Neoplasms, Thyroid Neoplasms, Carcinoma, Medullary

NCT00500292 2018-01-25

A Phase II Study of 2 Doses of ZD6474 (Vandetanib) in Combination With FOLFOX vs FOLFOX Alone for the Treatment of Colorectal Cancer

Phase 2 Completed

109 enrolled 8 charts

Neoplasms

NCT00508001 2016-10-10

Phase II Study of Best Support Care (BSC) Plus ZD6474(Vandetanib) in Patients With Inoperable Hepatocellular Carcinoma (HCC)

Phase 2 Completed

67 enrolled 12 charts

Gastrointestinal

Carcinoma, Hepatocellular, Neoplasms

NCT01372813 2015-10-23

Vandetanib to Treat Advanced Kidney Cancer

Phase 2 Terminated

3 enrolled 10 charts

Carcinoma, Renal Cell, Kidney Neoplasms, Neoplasms