Clinical Trials Browser

Neoplasms × Denosumab × Clear all

Breast Diseases, Breast Neoplasms, Neoplasms

NCT01345019 2022-11-08

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

Other hematologic neoplasmPlasma cellSarcoma

Blood Protein Disorders, Bone Diseases, Bone Marrow Diseases, Bone Neoplasms, Hematologic Diseases, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Neoplastic Processes, Paraproteinemias, Spinal Cord Compression, Hematologic Neoplasms, Fractures, Bone, Neoplasms, Plasma Cell

NCT00680992 2022-09-22

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

Phase 2 Completed

535 enrolled 16 charts

Giant Cell Tumors, Neoplasms, Giant Cell Tumor of Bone

NCT01624766 2021-02-25

Everolimus and Anakinra or Denosumab in Treating Participants With Relapsed or Refractory Advanced Cancers

Phase 1 Completed

57 enrolled

Neoplasm Metastasis, Neoplasms, Recurrence

NCT01545648 2020-01-02

Pilot Study to Evaluate the Impact of Denosumab on Disseminated Tumor Cells (DTC) in Patients With Early Stage Breast Cancer

Phase 2 Terminated

4 enrolled 7 charts

Tumor-Agnostic

Neoplasms

NCT01419717 2019-09-24

Open-Label Access Protocol of Denosumab for Subjects With Advanced Cancer

Phase 3 Completed

129 enrolled 10 charts

BreastGenitourinary

Breast Neoplasms, Neoplasms, Prostatic Neoplasms

NCT00838201 2018-10-18

Extension Study to Evaluate Long Term Safety of Denosumab in Subjects Undergoing ADT for Non-Metastatic Prostate Cancer

Phase 3 Completed

384 enrolled 8 charts

Genitourinary

Carcinoma, Neoplasms, Prostatic Neoplasms

NCT00896454 2018-10-17

Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

Phase 2 Completed

33 enrolled 22 charts

BreastGastrointestinalGenitourinaryHead & NeckLymphoidPlasma cellThoracic

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Endocrine Gland Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Hypercalcemia, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Parathyroid Neoplasms, Thyroid Neoplasms

NCT03415477 2018-01-30

Deno-ABC

Phase 1/2 Completed

6 enrolled

Fractures, Spontaneous, Neoplasms, Recurrence, Bone Cysts, Aneurysmal

NCT00925600 2017-05-30

Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss

Phase 3 Completed

769 enrolled 21 charts

Genitourinary

Bone Diseases, Metabolic, Cataract, Neoplasms, Osteoporosis, Prostatic Neoplasms

NCT00950911 2014-02-11

Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only

Phase 3 Completed

35 enrolled 8 charts

BreastGenitourinaryPlasma cell

Breast Neoplasms, Multiple Myeloma, Neoplasms, Prostatic Neoplasms

NCT00091832 2014-01-28

Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer

Phase 2 Completed

255 enrolled 34 charts

Breast

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

Clinical Trials

BRCA-P

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

Everolimus and Anakinra or Denosumab in Treating Participants With Relapsed or Refractory Advanced Cancers

Pilot Study to Evaluate the Impact of Denosumab on Disseminated Tumor Cells (DTC) in Patients With Early Stage Breast Cancer

Open-Label Access Protocol of Denosumab for Subjects With Advanced Cancer

Extension Study to Evaluate Long Term Safety of Denosumab in Subjects Undergoing ADT for Non-Metastatic Prostate Cancer

Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

Deno-ABC

Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss

Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only

Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer