Announcements Trials
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Phase

Phase 3 3Phase 2/3 1Phase 1/2 1

Status

Completed 5Withdrawn 2

Sponsor Class

INDUSTRY 5

Study Type

Interventional 5

Sponsor

Cancer Type

Head & Neck 2Plasma cell 1Other hematologic neoplasm 1Other 1Lymphoid 1Gastrointestinal 1

Conditions

Stomatitis 9Lymphoma, Non-Hodgkin 7Lymphoma 7Leukemia 7Hodgkin Disease 7Multiple Myeloma 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Neoplasms 5Leukemia, Myeloid, Acute 5Mucositis 4Leukemia, Lymphocytic, Chronic, B-Cell 4Neoplasms, Plasma Cell 3Lymphoma, Mantle-Cell 3Lymphoma, Large-Cell, Immunoblastic 3Lymphoma, Large B-Cell, Diffuse 3Lymphoma, Follicular 3Lymphoma, B-Cell, Marginal Zone 3Head and Neck Neoplasms 3Burkitt Lymphoma 3Blast Crisis 3Recurrence 2Leukemia, Myeloid, Chronic-Phase 2Leukemia, Myeloid, Accelerated Phase 2Graft vs Host Disease 2Drug-Related Side Effects and Adverse Reactions 2Xerostomia 1Sezary Syndrome 1Sarcoma 1Radiation Injuries 1Primary Myelofibrosis 1

Interventions

Gemcitabine 109Paclitaxel 92Carboplatin 79pembrolizumab 75Bevacizumab 75Surveys and Questionnaires 70Docetaxel 69Cisplatin 67Nivolumab 48Exercise 48Capecitabine 48Cyclophosphamide 47Sorafenib 43Fluorouracil 43Irinotecan 42Pemetrexed 37Albumin-Bound Paclitaxel 35Radiotherapy 34Dexamethasone 34Blood Specimen Collection 34Oxaliplatin 31Leucovorin 31Erlotinib Hydrochloride 31trametinib 30130-nm albumin-bound paclitaxel 29Cetuximab 28Therapeutics 26Ipilimumab 26Standard of Care 25Methods 25

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × Neoplasms × Fibroblast Growth Factor 7 × Clear all
NCT00626639 2017-06-21

A Study of Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy and Concurrent Chemotherapy

Swedish Orphan Biovitrum

Phase 1/2 Completed
5 enrolled 8 charts
Head & NeckOther

Head and Neck Neoplasms, Neoplasms, Mucositis

NCT00131638 2016-12-16

A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer

Amgen

Phase 3 Completed
241 enrolled
Head & Neck

Head and Neck Neoplasms, Neoplasms, Stomatitis

NCT00434161 2015-03-30

A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Multiple Myeloma

Swedish Orphan Biovitrum

Phase 3 Completed
281 enrolled 27 charts
Plasma cell

Cataract, Multiple Myeloma, Neoplasms, Stomatitis

NCT00109031 2014-09-15

Palifermin for the Reduction of Oral Mucositis in Single-dose Evaluation (PROMISE)

Swedish Orphan Biovitrum

Phase 3 Completed
47 enrolled 19 charts
LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Neoplasms

NCT00393822 2014-07-15

A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Stage 2B or 3 Locally Advanced, Colon Cancer

Amgen

Phase 2/3 Completed
100 enrolled
Gastrointestinal

Colonic Neoplasms, Neoplasms, Stomatitis

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