Announcements Trials
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Phase

Phase 1 3Phase 2 1

Status

Completed 6Unknown 5Recruiting 3Withdrawn 1Terminated 1

Sponsor Class

OTHER 5INDUSTRY 1

Study Type

Interventional 4Observational 2

Sponsor

Cancer Type

Tumor-Agnostic 2Thoracic 1CNS 1

Conditions

Polycystic Ovary Syndrome 91Breast Neoplasms 21Insulin Resistance 18Obesity 14Prostatic Neoplasms 10Pancreatic Neoplasms 8Endometrial Neoplasms 7Neoplasms 6Infertility 6Anovulation 6Neoplasm Metastasis 5Colorectal Neoplasms 5Rectal Neoplasms 4Hyperandrogenism 4Weight Loss 3Squamous Cell Carcinoma of Head and Neck 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Lung Neoplasms 3Leukemia, Lymphocytic, Chronic, B-Cell 3Hyperinsulinism 3Head and Neck Neoplasms 3Diabetes Mellitus, Type 2 3Diabetes Mellitus 3Carcinoma, Non-Small-Cell Lung 3Uterine Cervical Neoplasms 2Recurrence 2Rare Diseases 2Premature Birth 2Overweight 2Ovarian Neoplasms 2

Interventions

Gemcitabine 109Paclitaxel 92Carboplatin 79pembrolizumab 75Bevacizumab 75Surveys and Questionnaires 70Docetaxel 69Cisplatin 67Nivolumab 48Exercise 48Capecitabine 48Cyclophosphamide 47Sorafenib 43Fluorouracil 43Irinotecan 42Pemetrexed 37Albumin-Bound Paclitaxel 35Radiotherapy 34Dexamethasone 34Blood Specimen Collection 34Oxaliplatin 31Leucovorin 31Erlotinib Hydrochloride 31trametinib 30130-nm albumin-bound paclitaxel 29Cetuximab 28Therapeutics 26Ipilimumab 26Standard of Care 25Methods 25

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Completed × Neoplasms × Metformin × Clear all
NCT07628556 2026-06-05

Antidiabetic Medications and Risk of Cancer

University of Pecs

Completed
74,799 enrolled

Diabetes Mellitus, Type 2, Neoplasms

NCT03017833 2023-10-04

Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers

M.D. Anderson Cancer Center

Phase 1 Completed
31 enrolled
Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT01528046 2023-01-13

Metformin in Children With Relapsed or Refractory Solid Tumors

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Completed
26 enrolled
CNS

Brain Neoplasms, Neoplasms, Recurrence

NCT03086733 2020-08-19

Metcore

University Health Network, Toronto

Phase 2 Completed
28 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT01442870 2017-05-09

Evaluation of Clinical Safety of Combining Metformin With Anticancer Chemotherapy

Tufts Medical Center

Phase 1 Completed
105 enrolled
Tumor-Agnostic

Neoplasms

NCT01195259 2013-10-28

Malignancy Meta Analysis for BRL49653

GlaxoSmithKline

Completed
1 enrolled

Diabetes Mellitus, Type 2, Neoplasms

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