Announcements Trials
Browse Landscape

Phase

Phase 3 3Phase NA 1Phase 2/3 1Phase 2 1Phase 1 1

Status

Completed 3Unknown 2Withdrawn 1Terminated 1Suspended 1

Sponsor Class

OTHER 8

Study Type

Interventional 7Observational 1

Sponsor

Cancer Type

Tumor-Agnostic 1Other hematologic neoplasm 1Other 1Classical hematology 1

Conditions

Pain 11Neoplasms 8Cancer Pain 7Pain, Postoperative 2Pain, Intractable 2Lymphoma, Follicular 2Leukemia 2Waldenstrom Macroglobulinemia 1Vomiting 1Urinary Bladder Neoplasms 1Thrombocythemia, Essential 1Stomatitis 1Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 1Squamous Cell Carcinoma of Head and Neck 1Spinal Surgery 1Sleep Wake Disorders 1Signs and Symptoms 1Sezary Syndrome 1Rectal Neoplasms 1Primary Myelofibrosis 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Precancerous Conditions 1Postoperative Complications 1Polycythemia Vera 1Pdgfra-Associated Chronic Eosinophilic Leukemia 1Pathologic Processes 1Pain Related to Cancer 1Opioid-Related Disorders 1Neurologic Manifestations 1

Interventions

pembrolizumab 185Gemcitabine 170Paclitaxel 152Carboplatin 137Bevacizumab 128Surveys and Questionnaires 118Cisplatin 115Docetaxel 114Blood Specimen Collection 110Cyclophosphamide 109Exercise 108Nivolumab 98Fluorouracil 90Capecitabine 86Dexamethasone 81Radiotherapy 80Irinotecan 74Standard of Care 69Pemetrexed 68Oxaliplatin 68Leucovorin 64Drug Therapy 64Cetuximab 60Erlotinib Hydrochloride 56Sorafenib 53atezolizumab 52Ipilimumab 51Doxorubicin 50trametinib 47Interviews as Topic 47

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

8 trials
RecentStart dateEnrollment
Neoplasms × Methadone × Clear all
NCT06940570 2025-10-23

MATCH

University of Texas Southwestern Medical Center

Phase 3 Suspended
60 enrolled
Classical hematologyOtherOther hematologic neoplasm

Bone Marrow Failure Disorders, Anemia, Aplastic, Leukemia, Neoplasms, Pain, Intractable, Mucositis

NCT05325164 2022-12-05

METHADOPT

Ottawa Hospital Research Institute

Phase 3 Withdrawn

Cancer Pain, Adenocarcinoma, Neoplasms

NCT03324815 2017-10-30

Methadone Associated With Morphine for Cancer Pain

Federal University of São Paulo

Phase NA Unknown
40 enrolled

Neoplasms, Pain

NCT00125294 2017-09-25

Sublingual Methadone for the Management of Cancer Breakthrough Pain

AHS Cancer Control Alberta

Phase 1 Completed
10 enrolled

Cancer Pain, Neoplasms, Pain, Breakthrough Pain

NCT01946555 2016-04-14

RER

Mario Negri Institute for Pharmacological Research

Completed
150 enrolled

Cancer Pain, Neoplasms, Neuralgia

NCT00573937 2016-02-19

Methadone Versus Morphine for Cancer-Related Pain

Mayo Clinic

Phase 2 Terminated
1 enrolled 2 charts

Neoplasms, Pain

NCT00184496 2014-02-28

Switching From Morphine to Methadone. A Clinical, Pharmacological and Pharmacogenetic Study

Norwegian University of Science and Technology

Phase 3 Completed
42 enrolled
Tumor-Agnostic

Neoplasms

NCT00525967 2007-09-06

Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain

Faculdade de Medicina do ABC

Phase 2/3 Unknown
50 enrolled

Cancer Pain, Neoplasms, Pain

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