Announcements Trials
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Phase

Phase EARLY_PHASE1 1Phase 2 1Phase 1 1

Status

Completed 3

Sponsor Class

INDUSTRY 2OTHER 1

Study Type

Interventional 3

Sponsor

Cancer Type

Tumor-Agnostic 1Other hematologic neoplasm 1Breast 1

Conditions

Breast Neoplasms 17Neoplasm Metastasis 8Carcinoma, Non-Small-Cell Lung 6Glioblastoma 5Triple Negative Breast Neoplasms 4Lymphoma, Mantle-Cell 4Lymphoma, Follicular 4Colorectal Neoplasms 4Recurrence 3Pancreatic Neoplasms 3Ovarian Neoplasms 3Neoplasms 3Lymphoma, Large B-Cell, Diffuse 3Squamous Cell Carcinoma of Head and Neck 2Solid Tumors 2Lymphoma 2Lung Neoplasms 2Leukemia, Myeloid, Acute 2Hereditary Sensory and Autonomic Neuropathies 2Head and Neck Neoplasms 2Endometrial Neoplasms 2Brain Neoplasms 2Waldenstrom Macroglobulinemia 1Unspecified Adult Solid Tumor, Protocol Specific 1Tongue Neoplasms 1Thymoma 1Stomach Neoplasms 1Salivary Gland Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pre-menopausal Breast Cancer 1

Interventions

Gemcitabine 109Paclitaxel 92Carboplatin 79pembrolizumab 75Bevacizumab 75Surveys and Questionnaires 70Docetaxel 69Cisplatin 67Nivolumab 48Exercise 48Capecitabine 48Cyclophosphamide 47Sorafenib 43Fluorouracil 43Irinotecan 42Pemetrexed 37Albumin-Bound Paclitaxel 35Radiotherapy 34Dexamethasone 34Blood Specimen Collection 34Oxaliplatin 31Leucovorin 31Erlotinib Hydrochloride 31trametinib 30130-nm albumin-bound paclitaxel 29Cetuximab 28Therapeutics 26Ipilimumab 26Standard of Care 25Methods 25

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Neoplasms × NVP-BKM120 × Clear all
NCT01285466 2020-12-09

A Trial of Oral BEZ235 and BKM120 in Combination With Paclitaxel With or Without Trastuzumab

Novartis

Phase 1 Completed
110 enrolled
Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT01833169 2018-10-19

SIGNATURE

Novartis

Phase 2 Completed
146 enrolled 17 charts
Other hematologic neoplasm

Neoplasms, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT01513356 2014-04-02

Pharmacodynamic Study of BKM120 in Breast Cancer

Grupo Hospital de Madrid

Phase EARLY_PHASE1 Completed
20 enrolled
Breast

Breast Neoplasms, Neoplasms

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