Announcements Trials
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Phase

Phase 1 3

Status

Terminated 2Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Breast 2Tumor-Agnostic 1Sarcoma 1Myeloid 1Lymphoid 1Head & Neck 1Genitourinary 1CNS 1

Conditions

Brain Neoplasms 4Sarcoma 3Neoplasms 3Recurrence 2Ovarian Neoplasms 2Neoplasm Metastasis 2Nasopharyngeal Carcinoma 2Medulloblastoma 2Glioblastoma 2Central Nervous System Neoplasms 2Breast Neoplasms 2Astrocytoma 2Urologic Neoplasms 1Thyroid Neoplasms 1Spinal Cord Neoplasms 1Solid Tumors 1Solid Tumor Malignancies 1Soft Tissue Neoplasms 1Pharyngeal Neoplasms 1Osteosarcoma 1Optic Nerve Glioma 1Neurofibromatosis 2 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroectodermal Tumors, Primitive 1Neuroectodermal Tumors 1Neuroblastoma 1Neoplasms, Mesothelial 1Myelodysplastic Syndromes 1Multiple Acyl Coenzyme A Dehydrogenase Deficiency 1Mouth Neoplasms 1

Interventions

pembrolizumab 82Paclitaxel 71Gemcitabine 66Carboplatin 61Cisplatin 46Docetaxel 44Bevacizumab 41Nivolumab 33Irinotecan 31Fluorouracil 29Pemetrexed 28Cyclophosphamide 26Cetuximab 26Capecitabine 26Erlotinib Hydrochloride 22venetoclax 21trametinib 21Leucovorin 20Sorafenib 17Albumin-Bound Paclitaxel 17Afatinib 17130-nm albumin-bound paclitaxel 17Topotecan 16Radiotherapy 16Oxaliplatin 16fludarabine 15regorafenib 14budigalimab 14atezolizumab 14Ipilimumab 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Neoplasms × Valproic Acid × Clear all
NCT01552434 2026-05-15

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

M.D. Anderson Cancer Center

Phase 1 Terminated
154 enrolled
BreastCNSGenitourinaryHead & NeckLymphoidMyeloidSarcoma

Breast Neoplasms, Carcinoma, Transitional Cell, Endocrine Gland Neoplasms, Castleman Disease, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms, Pharyngeal Neoplasms, Recurrence, Sarcoma, Soft Tissue Neoplasms, Thyroid Neoplasms, Urologic Neoplasms, Neurofibromatosis 2, Lymphangioleiomyomatosis, Neoplasms, Mesothelial, Erdheim-Chester Disease

NCT00246103 2017-02-23

Phase I Trial of Valproic Acid and Epirubicin in Solid Tumor Malignancies

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Completed
82 enrolled
Tumor-Agnostic

Neoplasms

NCT01007695 2016-07-20

VAST

University of Utah

Phase 1 Terminated
31 enrolled
Breast

Breast Neoplasms, Neoplasms

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