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Phase

Phase 2 10Phase 3 5Phase 1 4Phase 4 2Phase 1/2 2Phase NA 1Phase EARLY_PHASE1 1

Status

Completed 3Terminated 1

Sponsor Class

INDUSTRY 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4Sarcoma 3Genitourinary 3Other hematologic neoplasm 1Lymphoid 1Gastrointestinal 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 29Lymphoma, Large B-Cell, Diffuse 19Lymphoma 15Burkitt Lymphoma 15Neuroblastoma 12Lymphoma, Non-Hodgkin 11Recurrence 10Lymphoma, Follicular 9Leukemia 9Lymphoma, T-Cell, Peripheral 6Lymphoma, T-Cell 6Lymphoma, B-Cell 6Leukemia, Biphenotypic, Acute 6Brain Neoplasms 6Lymphoma, Mantle-Cell 5Leukemia, Lymphocytic, Chronic, B-Cell 5Central Nervous System Neoplasms 5Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Neoplasms 4Lymphoma, Large-Cell, Anaplastic 4Lymphoma, B-Cell, Marginal Zone 4Hodgkin Disease 4HIV Infections 4Acquired Immunodeficiency Syndrome 4Sarcoma, Kaposi 3Sarcoma, Ewing 3Sarcoma 3Medulloblastoma 3Leukemia, Myeloid, Acute 3Hematologic Neoplasms 3

Interventions

pembrolizumab 82Paclitaxel 71Gemcitabine 66Carboplatin 61Cisplatin 46Docetaxel 44Bevacizumab 41Nivolumab 33Irinotecan 31Fluorouracil 29Pemetrexed 28Cyclophosphamide 26Cetuximab 26Capecitabine 26Erlotinib Hydrochloride 22venetoclax 21trametinib 21Leucovorin 20Sorafenib 17Albumin-Bound Paclitaxel 17Afatinib 17130-nm albumin-bound paclitaxel 17Topotecan 16Radiotherapy 16Oxaliplatin 16fludarabine 15regorafenib 14budigalimab 14atezolizumab 14Ipilimumab 14

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1 × Neoplasms × Vincristine × Clear all
NCT02085148 2024-04-22

A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy

Bayer

Phase 1 Completed
62 enrolled
CNSGastrointestinalGenitourinarySarcoma

Neoplasms, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Hepatoblastoma

NCT01528046 2023-01-13

Metformin in Children With Relapsed or Refractory Solid Tumors

H. Lee Moffitt Cancer Center and Research Institute

Phase 1 Completed
26 enrolled
CNS

Brain Neoplasms, Neoplasms, Recurrence

NCT01222780 2020-01-18

To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer

Acrotech Biopharma Inc.

Phase 1 Completed
22 enrolled
CNSGenitourinaryLymphoidOther hematologic neoplasmSarcoma

Brain Neoplasms, Leukemia, Lymphoma, Neoplasms, Wilms Tumor, Neuroblastoma, Sarcoma, Hematologic Neoplasms

NCT00960063 2018-08-27

A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Pediatric Participants With Advanced Solid Tumors (P05883, MK-7454-006)

Merck Sharp & Dohme LLC

Phase 1 Terminated
4 enrolled 8 charts
CNSGenitourinarySarcoma

Bone Neoplasms, Carcinoma, Renal Cell, Neoplasms, Neuroblastoma

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