Announcements Trials
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Phase

Phase 1 5Phase 1/2 1

Status

Completed 6Withdrawn 1

Sponsor Class

INDUSTRY 6

Study Type

Interventional 6

Sponsor

Cancer Type

Tumor-Agnostic 3Thoracic 2Lymphoid 1Gynecologic 1

Conditions

Neoplasms 6Endometrial Neoplasms 2Carcinoma, Non-Small-Cell Lung 2Breast Neoplasms 2Solid Tumor Cancers 1Ovarian Neoplasms 1Neoplasm Metastasis 1Lymphoma 1Glioblastoma 1

Interventions

Gemcitabine 109Paclitaxel 92Carboplatin 79pembrolizumab 75Bevacizumab 75Surveys and Questionnaires 70Docetaxel 69Cisplatin 67Nivolumab 48Exercise 48Capecitabine 48Cyclophosphamide 47Sorafenib 43Fluorouracil 43Irinotecan 42Pemetrexed 37Albumin-Bound Paclitaxel 35Radiotherapy 34Dexamethasone 34Blood Specimen Collection 34Oxaliplatin 31Leucovorin 31Erlotinib Hydrochloride 31trametinib 30130-nm albumin-bound paclitaxel 29Cetuximab 28Therapeutics 26Ipilimumab 26Standard of Care 25Methods 25

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Completed × Neoplasms × XL147 × Clear all
NCT01587040 2022-04-19

Open Label Treatment Extension Study With SAR245408 or SAR245409 as a Monotherapy or as a Combination Regimen

Sanofi

Phase 1/2 Completed
61 enrolled 13 charts
Tumor-Agnostic

Neoplasms

NCT01943838 2016-04-22

A Study of the Safety and Pharmacokinetics of SAR245408 Tablets in Patients With Solid Tumors or Lymphoma

Sanofi

Phase 1 Completed
18 enrolled
Tumor-Agnostic

Neoplasms

NCT01392924 2014-12-03

Safety and Pharmacokinetics of SAR245408 Daily Oral in Patients With Solid Tumors

Sanofi

Phase 1 Completed
10 enrolled
Tumor-Agnostic

Neoplasms

NCT00756847 2013-04-10

Safety Study of XL147 (SAR245408), in Combination With Paclitaxel and Carboplatin in Adults With Solid Tumors

Sanofi

Phase 1 Completed
52 enrolled
GynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT00486135 2013-02-01

Study of the Safety and Pharmacokinetics of XL147 (SAR245408) in Adults With Solid Tumors or Lymphoma

Sanofi

Phase 1 Completed
118 enrolled
Lymphoid

Lymphoma, Neoplasms

NCT00692640 2012-03-23

Safety Study of XL147 (SAR245408) in Combination With Erlotinib in Adults With Solid Tumors

Sanofi

Phase 1 Completed
35 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms

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