Announcements Trials
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Phase

Phase 2 3Phase 3 1

Status

Completed 4Terminated 3Unknown 1

Sponsor Class

INDUSTRY 3OTHER_GOV 1

Study Type

Interventional 4

Sponsor

Cancer Type

Dermatologic 2Tumor-Agnostic 1Thoracic 1

Conditions

Melanoma 12Colorectal Neoplasms 9Lung Neoplasms 6Carcinoma, Non-Small-Cell Lung 5Triple Negative Breast Neoplasms 4Neoplasms 4Neoplasm Metastasis 4Pancreatic Neoplasms 3Colonic Neoplasms 3Skin Neoplasms 2Skin Diseases 2Rectal Neoplasms 2Brain Neoplasms 2Biliary Tract Neoplasms 2Spinocerebellar Degenerations 1Solid Tumors Harboring a BRAF V600 Mutation 1Solid Tumor 1Soft Tissue Neoplasms 1Recurrence 1Peripheral Nervous System Neoplasms 1Parkinson Disease 4, Autosomal Dominant Lewy Body 1Ovarian Neoplasms 1Noonan Syndrome 5 1Neurofibromatosis 1 1Neurofibromatoses 1Neurofibroma, Plexiform 1Neurofibroma 1Multiple Myeloma 1Leukemia, Myeloid, Acute 1Hereditary Sensory and Autonomic Neuropathies 1

Interventions

Gemcitabine 109Paclitaxel 92Carboplatin 79pembrolizumab 75Bevacizumab 75Surveys and Questionnaires 70Docetaxel 69Cisplatin 67Nivolumab 48Exercise 48Capecitabine 48Cyclophosphamide 47Sorafenib 43Fluorouracil 43Irinotecan 42Pemetrexed 37Albumin-Bound Paclitaxel 35Radiotherapy 34Dexamethasone 34Blood Specimen Collection 34Oxaliplatin 31Leucovorin 31Erlotinib Hydrochloride 31trametinib 30130-nm albumin-bound paclitaxel 29Cetuximab 28Therapeutics 26Ipilimumab 26Standard of Care 25Methods 25

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × Neoplasms × binimetinib × Clear all
NCT03915951 2026-03-24

An Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung Cancer

Pfizer

Phase 2 Completed
98 enrolled 18 charts 1 FDA
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT01909453 2026-02-27

COLUMBUS

Pfizer

Phase 3 Completed
921 enrolled 48 charts 1 FDA
Dermatologic

Melanoma, Neoplasm Metastasis, Neoplasms, Skin Diseases, Skin Neoplasms

NCT05304546 2025-07-22

MK3475-C01

Sheba Medical Center

Phase 2 Completed
1 enrolled
Dermatologic

Melanoma, Neoplasms

NCT03271047 2022-01-04

Study of Binimetinib + Nivolumab Plus or Minus Ipilimumab in Patients With Previously Treated Microsatellite-stable (MSS) Metastatic Colorectal Cancer With RAS Mutation

Pfizer

Phase 2 Completed
75 enrolled 17 charts
Tumor-Agnostic

Neoplasms

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