Announcements Trials
Browse Landscape

Phase

Phase 1 5Phase 2 1

Status

Completed 6

Sponsor Class

INDUSTRY 6

Study Type

Interventional 6

Sponsor

Cancer Type

Tumor-Agnostic 2Thoracic 2Gastrointestinal 2

Conditions

Neoplasms 6Neoplasm Metastasis 6Pancreatic Neoplasms 2Lung Neoplasms 1Lung Diseases 1Colorectal Neoplasms 1Carcinoma, Non-Small-Cell Lung 1Carcinoma 1

Interventions

Gemcitabine 109Paclitaxel 92Carboplatin 79pembrolizumab 75Bevacizumab 75Surveys and Questionnaires 70Docetaxel 69Cisplatin 67Nivolumab 48Exercise 48Capecitabine 48Cyclophosphamide 47Sorafenib 43Fluorouracil 43Irinotecan 42Pemetrexed 37Albumin-Bound Paclitaxel 35Radiotherapy 34Dexamethasone 34Blood Specimen Collection 34Oxaliplatin 31Leucovorin 31Erlotinib Hydrochloride 31trametinib 30130-nm albumin-bound paclitaxel 29Cetuximab 28Therapeutics 26Ipilimumab 26Standard of Care 25Methods 25

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Completed × Neoplasms × demcizumab × Clear all
NCT00744562 2020-09-10

A Phase 1 Dose Escalation Study of OMP-21M18 in Subjects With Solid Tumors

Mereo BioPharma

Phase 1 Completed
42 enrolled
Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT01189929 2020-09-09

A Study of Gemcitabine and Demcizumab (OMP-21M18) With or Without Abraxane® as 1st-line Treatment in Subjects With Locally Advanced or Metastatic Pancreatic Cancer

Mereo BioPharma

Phase 1 Completed
57 enrolled
Gastrointestinal

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT01189942 2020-09-09

A Study of FOLFIRI Plus OMP-21M18 as 1st or 2nd-line Treatment in Subjects With Metastatic Colorectal Cancer

Mereo BioPharma

Phase 1 Completed
18 enrolled
Gastrointestinal

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT01189968 2020-09-09

A Study of Carboplatin and Pemetrexed Plus Demcizumab (OMP-21M18) in Subjects With Non-Squamous Non-Small Cell Lung Cancer

Mereo BioPharma

Phase 1 Completed
50 enrolled
Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms

NCT02259582 2020-09-09

DENALI

Mereo BioPharma

Phase 2 Completed
82 enrolled 10 charts
Thoracic

Carcinoma, Lung Diseases, Lung Neoplasms, Neoplasm Metastasis, Neoplasms

NCT02722954 2020-08-11

A Phase 1b Study of Demcizumab Plus Pembrolizumab in Locally Advanced or Metastatic Solid Tumors

Mereo BioPharma

Phase 1 Completed
29 enrolled
Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

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