Announcements Trials
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Phase

Phase 2 2Phase 3 1

Status

Completed 3Terminated 2Unknown 1Active not recruiting 1

Sponsor Class

INDUSTRY 2OTHER_GOV 1

Study Type

Interventional 3

Sponsor

Cancer Type

Dermatologic 2Thoracic 1

Conditions

Melanoma 12Colorectal Neoplasms 9Neoplasm Metastasis 4Neoplasms 3Carcinoma, Non-Small-Cell Lung 2Solid Tumors Harboring a BRAF V600 Mutation 1Skin Neoplasms 1Skin Diseases 1Recurrence 1Pancreatic Neoplasms 1Multiple Myeloma 1Lung Neoplasms 1Gastrointestinal Neoplasms 1Digestive System Neoplasms 1Colonic Neoplasms 1Brain Neoplasms 1Advanced BRAF Mutant Cancers 1

Interventions

Gemcitabine 109Paclitaxel 92Carboplatin 79pembrolizumab 75Bevacizumab 75Surveys and Questionnaires 70Docetaxel 69Cisplatin 67Nivolumab 48Exercise 48Capecitabine 48Cyclophosphamide 47Sorafenib 43Fluorouracil 43Irinotecan 42Pemetrexed 37Albumin-Bound Paclitaxel 35Radiotherapy 34Dexamethasone 34Blood Specimen Collection 34Oxaliplatin 31Leucovorin 31Erlotinib Hydrochloride 31trametinib 30130-nm albumin-bound paclitaxel 29Cetuximab 28Therapeutics 26Ipilimumab 26Standard of Care 25Methods 25

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Neoplasms × encorafenib × Clear all
NCT03915951 2026-03-24

An Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung Cancer

Pfizer

Phase 2 Completed
98 enrolled 18 charts 1 FDA
Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT01909453 2026-02-27

COLUMBUS

Pfizer

Phase 3 Completed
921 enrolled 48 charts 1 FDA
Dermatologic

Melanoma, Neoplasm Metastasis, Neoplasms, Skin Diseases, Skin Neoplasms

NCT05304546 2025-07-22

MK3475-C01

Sheba Medical Center

Phase 2 Completed
1 enrolled
Dermatologic

Melanoma, Neoplasms

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