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Phase

Phase EARLY_PHASE1 1Phase 1 1

Status

Not yet recruiting 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Tumor-Agnostic 1CNS 1

Conditions

Leukemia, Myeloid, Acute 10Myelodysplastic Syndromes 4Mycoses 4Hematologic Neoplasms 4Neoplasms 2Leukemia 2Brain Neoplasms 2Triple Negative Breast Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Neutropenia 1Neoplasm, Residual 1Myelodysplastic-Myeloproliferative Diseases 1Mucormycosis 1Leukemia, Myeloid 1Invasive Fungal Infections 1Glioma 1Glioblastoma 1Genetic Predisposition to Disease 1Candidiasis 1Bronchiolitis Obliterans Syndrome 1Breast Neoplasms 1Bone Marrow Neoplasms 1Bone Marrow Failure Disorders 1Aspergillosis 1Anemia, Aplastic 1

Interventions

pembrolizumab 185Gemcitabine 170Paclitaxel 152Carboplatin 137Bevacizumab 128Surveys and Questionnaires 118Cisplatin 115Docetaxel 114Blood Specimen Collection 110Cyclophosphamide 109Exercise 108Nivolumab 98Fluorouracil 90Capecitabine 86Dexamethasone 81Radiotherapy 80Irinotecan 74Standard of Care 69Pemetrexed 68Oxaliplatin 68Leucovorin 64Drug Therapy 64Cetuximab 60Erlotinib Hydrochloride 56Sorafenib 53atezolizumab 52Ipilimumab 51Doxorubicin 50trametinib 47Interviews as Topic 47

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Neoplasms × posaconazole × Clear all
NCT03763396 2024-03-08

Azoles Targeting Recurrent High Grade Gliomas

University Health Network, Toronto

Phase EARLY_PHASE1 Not yet recruiting
30 enrolled
CNS

Brain Neoplasms, Glioma, Neoplasms

NCT01901172 2015-08-18

A Study of the Drug-Drug Interaction of RO5503781 and Posaconazole, the Relative Bioavailability of New Formulations of RO5503781 and the Food-Effect on the Pharmacokinetics of RO5503781 in Patients With Solid Tumors

Hoffmann-La Roche

Phase 1 Completed
61 enrolled
Tumor-Agnostic

Neoplasms

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