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Phase

Phase EARLY_PHASE1 1Phase 1 1

Status

Not yet recruiting 1Completed 1

Sponsor Class

OTHER 1INDUSTRY 1

Study Type

Interventional 2

Sponsor

Cancer Type

Tumor-Agnostic 1CNS 1

Conditions

Leukemia, Myeloid, Acute 10Myelodysplastic Syndromes 4Mycoses 4Hematologic Neoplasms 3Neoplasms 2Leukemia 2Brain Neoplasms 2Triple Negative Breast Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Neutropenia 1Neoplasm, Residual 1Myelodysplastic-Myeloproliferative Diseases 1Leukemia, Myeloid 1Invasive Fungal Infections 1Glioma 1Glioblastoma 1Genetic Predisposition to Disease 1Candidiasis 1Bronchiolitis Obliterans Syndrome 1Breast Neoplasms 1Bone Marrow Neoplasms 1Bone Marrow Failure Disorders 1Aspergillosis 1Anemia, Aplastic 1

Interventions

pembrolizumab 180Gemcitabine 168Paclitaxel 150Carboplatin 134Bevacizumab 126Cisplatin 113Docetaxel 112Cyclophosphamide 109Exercise 97Nivolumab 93Fluorouracil 88Capecitabine 85Dexamethasone 81Irinotecan 74Radiotherapy 68Oxaliplatin 68Pemetrexed 66Standard of Care 64Leucovorin 63Cetuximab 59Sorafenib 53Erlotinib Hydrochloride 53Drug Therapy 53Blood Specimen Collection 51Doxorubicin 50atezolizumab 48trametinib 47Ipilimumab 47Albumin-Bound Paclitaxel 44130-nm albumin-bound paclitaxel 42

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Interventional × Neoplasms × posaconazole × Clear all
NCT03763396 2024-03-08

Azoles Targeting Recurrent High Grade Gliomas

University Health Network, Toronto

Phase EARLY_PHASE1 Not yet recruiting
30 enrolled
CNS

Brain Neoplasms, Glioma, Neoplasms

NCT01901172 2015-08-18

A Study of the Drug-Drug Interaction of RO5503781 and Posaconazole, the Relative Bioavailability of New Formulations of RO5503781 and the Food-Effect on the Pharmacokinetics of RO5503781 in Patients With Solid Tumors

Hoffmann-La Roche

Phase 1 Completed
61 enrolled
Tumor-Agnostic

Neoplasms

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