Announcements Trials
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Phase

Phase 2 4Phase 1/2 3Phase 1 1

Status

Completed 2Terminated 1Recruiting 1

Sponsor Class

OTHER 2NETWORK 1INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

Tumor-Agnostic 1Genitourinary 1Gastrointestinal 1Dermatologic 1

Conditions

Carcinoma, Hepatocellular 23Carcinoma, Non-Small-Cell Lung 12Colorectal Neoplasms 8Biliary Tract Neoplasms 6Squamous Cell Carcinoma of Head and Neck 5Mesothelioma, Malignant 5Melanoma 5Liver Neoplasms 5Cholangiocarcinoma 5Urinary Bladder Neoplasms 4Prostatic Neoplasms 4Neoplasms 4Diabetes Mellitus, Insulin-Dependent, 12 4Neoplasm Metastasis 3Lung Neoplasms 3Head and Neck Neoplasms 3Fallopian Tube Neoplasms 3Carcinoma, Renal Cell 3Breast Neoplasms 3Triple Negative Breast Neoplasms 2Stomach Neoplasms 2Recurrence 2Ovarian Neoplasms 2Neoplasms, Germ Cell and Embryonal 2Mesothelioma 2Gallbladder Neoplasms 2Endometrial Neoplasms 2Adenocarcinoma Of Esophagus 2Vascular Neoplasms 1Uveal Melanoma 1

Interventions

Gemcitabine 53Bevacizumab 52Cyclophosphamide 49Docetaxel 42Carboplatin 40pembrolizumab 37Paclitaxel 36Fluorouracil 36Cisplatin 35Radiotherapy 31Oxaliplatin 31Capecitabine 29Irinotecan 28Dexamethasone 27Leucovorin 25Cetuximab 25Nivolumab 24Doxorubicin 22Drug Therapy 21Erlotinib Hydrochloride 20Pemetrexed 19durvalumab 18trametinib 17fludarabine 16atezolizumab 16Trastuzumab 16Sunitinib 16Rituximab 16Prednisone 16Sorafenib 15

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 2 × Neoplasms × tremelimumab × Clear all
NCT03911557 2025-11-12

Durvalumab and Tremelimumab Combination in Somatically Hypermutated Recurrent Solid Tumors

University of Kentucky

Phase 2 Completed
14 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Neoplasms

NCT02938793 2025-09-23

Durvalumab in Combination With Tremelimumab in Subjects With Advanced Rare Solid Tumors

Prisma Health-Upstate

Phase 2 Terminated
92 enrolled

Neoplasms, Rare Diseases

NCT03847649 2025-06-11

A Phase II Study of Durvalumab Treatment - Substudy A: In Patients Who Discontinued Prior Checkpoint Therapy Due to Immune Related Toxicity - Substudy B: For Continued Treatment (+/- Tremelimumab) of Patients Previously Enrolled to Completed CCTG Studies

Canadian Cancer Trials Group

Phase 2 Recruiting
60 enrolled
Tumor-Agnostic

Neoplasms

NCT00378482 2024-08-22

A Rollover Study for Patients Who Received Tremelimumab in Other Protocols, to Allow the Patients Access to Tremelimumab Until This Agent Becomes Commercially Available or Development is Discontinued.

AstraZeneca

Phase 2 Completed
37 enrolled 13 charts
DermatologicGastrointestinalGenitourinary

Carcinoma, Renal Cell, Melanoma, Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

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