Clinical Trials

CNSSarcoma

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT02437227 2026-05-12

PanRAF

31 enrolled 16 charts

Dermatologic

Melanoma, Neoplasms

NCT07217028 2026-05-11

Study Evaluating [18F]NOTA-ABY030 for Safety and Tolerability of Indeterminate Primary and/or Metastatic Disease in Head and Neck Squamous Cell Carcinoma

25 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Neoplasms

NCT07560943 2026-05-11

Safety and Tolerability of AI-Designed Pan-Cancer Neoantigen mRNA Vaccine (PAN-NeoVax) in Advanced Solid Tumors

Neoplasms

NCT07562815 2026-05-11

Safety and Tolerability of NCP-IL-22BP mRNA in Advanced Solid Tumors

Neoplasms

NCT07563972 2026-05-11

Intratumoral Macrophage Exosomes With Mechanobiological Reprogramming for Advanced Solid Tumors

Neoplasms

NCT04627246 2026-05-08

Personalized Vaccine With SOC Chemo Followed by Nivo in Pancreatic Cancer

14 enrolled

Adenocarcinoma, Neoplasms

NCT03560882 2026-05-06

A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignancies

MyeloidOther hematologic neoplasm

50 enrolled

Myelodysplastic Syndromes, Neoplasms, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT07567222 2026-05-06

Clinical Study of Novel Therapeutic Vaccine for Advanced Solid Tumors

54 enrolled

Neoplasms

NCT04084067 2026-04-30

Indocyanine Green (ICG) Guided Tumor Resection

CNSGastrointestinalGenitourinaryLymphoidSarcoma

230 enrolled

Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Lymphoma, Neoplasms, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma

NCT05887882 2026-04-24

PNOC028

Phase 1 Suspended

Neoplasms

NCT03696030 2026-04-23

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasms, Meningeal Carcinomatosis

NCT07538648 2026-04-20

A Phase II Clinical Study Evaluating the Effectiveness of Injectable NC527-X in Intraoperative Imaging for Patients With Solid Tumors

400 enrolled

Neoplasms

NCT05470283 2026-04-16

Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma

21 enrolled

Dermatologic

Melanoma, Neoplasms

NCT02379520 2026-04-15

HESTIA

32 enrolled

Neoplasms, Recurrence

NCT03403049 2026-04-13

Carbon Ion Radiation Therapy for Locally Advanced Pancreatic Cancer

14 enrolled

Gastrointestinal

Neoplasms, Pancreatic Neoplasms

NCT04488354 2026-04-08

Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T

16 enrolled

Burkitt Lymphoma, Lymphoma, Follicular, Waldenstrom Macroglobulinemia, Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Hematologic Neoplasms, Lymphoma, Mantle-Cell

NCT05544968 2026-04-03

Anti-CD30 biAb-AATC in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies

42 enrolled

Hodgkin Disease, Leukemia, Lymphoma, Neoplasms, Recurrence, Lymphoma, Large-Cell, Anaplastic

NCT07144085 2026-04-03

Application of ⁶⁸Ga-FXX489 (NNS309) PET/CT Imaging in Diagnosis of Tumor Diseases.

30 enrolled

Neoplasm Metastasis, Neoplasms

NCT07496073 2026-03-27

A Phase I, Single-arm, Open-label Clinical Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of CHT101 Cell Infusion in Adult Subjects With Recurrent or Progressive Malignant Primary Brain Tumors（CROWN）

30 enrolled

Brain Neoplasms, Neoplasms, Neurologic Manifestations

NCT03568058 2026-03-24

Personalized Immunotherapy in Adults With Advanced Cancers Immunotherapy in Adults With Advanced Cancers

25 enrolled 12 charts

Neoplasms

NCT06298357 2026-03-18

Virtual Reality Gaming for Exercise and Mindfulness Among Pediatric Cancer Rehabilitation

11 enrolled

Neoplasms

NCT01374620 2026-03-16

PAL-ANGI2

28 enrolled

Neoplasms

NCT07474168 2026-03-16

T Cell Receptor Gene-Engineered and Dominant Negative TGF-β Receptor T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor

Neoplasms

NCT01046487 2026-03-13

PALANGI3

DermatologicGastrointestinalSarcoma

26 enrolled

Uveal Melanoma, Chordoma, Carcinoma, Adenoid Cystic, Neoplasms, Desmoid Tumors, Dermatofibrosarcoma, Gastrointestinal Stromal Tumors

NCT07454031 2026-03-13

Intraperitoneal PX in Combination With Nab-Paclitaxel in Patients With Peritoneal Metastatic Mucinous Adenocarcinoma

22 enrolled

Neoplasm Metastasis, Neoplasms

NCT02780128 2026-03-10

NEPENTHE

Phase 1 Terminated

66 enrolled

Neoplasms, Neuroblastoma

NCT05707910 2026-03-09

Clinical Study of Therapeutic Immunological Agent for EBV-positive Advanced Malignant Tumors

6 enrolled

Neoplasms

NCT07454668 2026-03-06

Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases

20 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT07447856 2026-03-04

A Study Testing Topical Pain-Relieving Herbal Plasters in People Who Are Using Opioids for Their Pain

150 enrolled

Cancer Pain, Neoplasms, Pain

NCT03830320 2026-02-27

Positron Emission Tomography (PET) Imaging of Thrombosis

165 enrolled

COVID-19, Atrial Fibrillation, Neoplasms, Thrombosis

NCT07382817 2026-02-27

Phase 1 Study of JV-394 Autologous Anti-CD94 CAR T for r/r CD94+ T/NK Cell Neoplasms

33 enrolled

Lymphoid

Neoplasms, Lymphoma, T-Cell, Lymphoma, Extranodal NK-T-Cell

NCT03203525 2026-02-25

Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

38 enrolled

Neoplasms

NCT06104488 2026-02-25

A Study of Avutometinib for People With Solid Tumor Cancers

23 enrolled

Brain Neoplasms, Neoplasms, Neuroblastoma, Central Nervous System Neoplasms, Neurofibroma, Plexiform

NCT06524570 2026-02-18

iFOCUS

GastrointestinalGynecologicHead & Neck

Neoplasm Metastasis, Neoplasms

NCT03065062 2026-02-13

Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors

Phase 1 Suspended

75 enrolled

Head and Neck Neoplasms, Neoplasms, Pancreatic Neoplasms, Endometrial Neoplasms

NCT00586391 2026-02-06

CRETI-NH

14 enrolled

Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05421897 2026-01-29

RAPID

11 enrolled

Neoplasms, Neuroblastoma

NCT07348042 2026-01-16

Study of RGL-270 Single Drug and Combined With Adebelimab in Patients in Patients at High Risk of Recurrence After Radical Treatment of Malignant Solid Tumors

198 enrolled

Neoplasms

NCT05273554 2026-01-12

A Pilot Study to Assess Changes in Tumor Biology Following Second-line Treatment With Pembrolizumab Plus Lenvatinib in Patients With Advanced Pancreatic Ductal Adenocarcinoma

15 enrolled

Adenocarcinoma, Neoplasms

NCT03602157 2026-01-06

Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL

43 enrolled

DermatologicLymphoid

Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoproliferative Disorders, Mycosis Fungoides, Neoplasms, Sezary Syndrome, Lymphoma, T-Cell, Cutaneous, Lymphomatoid Papulosis

NCT02860676 2025-12-15

Extension Study of UC-961 (Cirmtuzumab) for Patients With Chronic Lymphocytic Leukemia Treated Previously With UC-961

3 enrolled 8 charts

Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell

NCT07257640 2025-12-10

IL-5 CAR-T Cell Therapy for Refractory/Relapsed Eosinophilic Leukemia

20 enrolled

Hematologic Diseases, Neoplasms

NCT07269899 2025-12-08

Reboot-107

12 enrolled

Neoplasms

NCT05859074 2025-12-03

A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer

DermatologicHead & NeckSarcoma

56 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Hemangiosarcoma, Melanoma, Neoplasm Metastasis, Neoplasms, Paget Disease, Extramammary, Sarcoma, Kaposi, Skin Neoplasms, Carcinoma, Merkel Cell, Adenocarcinoma, Sebaceous, Carcinoma, Skin Appendage

NCT06478251 2025-11-25

T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor