Clinical Trials Browser

Phase 1 × Completed × Neoplasms × Clear all

NCT00600496 2026-05-27

A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)

Phase 1 Completed

BreastDermatologicGastrointestinalGenitourinaryThoracic

Breast Neoplasms, Colonic Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms

NCT03611595 2026-05-27

Cabozantinib in Combination With 13-cis-Retinoic Acid in Children With Relapsed or Refractory Solid Tumors

Phase 1 Completed

Neoplasms

NCT01445509 2026-05-22

Dasatinib in Combination With Bevacizumab to Treat Advanced Solid Tumors

Phase 1 Completed

Neoplasms

NCT04130542 2026-05-19

Phase 1 Trial of LVGN6051 as Single Agent and in Combination With Keytruda (Pembrolizumab) in Advanced or Metastatic Malignancy

Phase 1 Completed

Neoplasms

NCT04635995 2026-05-19

Phase 1 Trial of LVGN7409 (CD40 Agonist Antibody) as Single Agent and Combination Therapies in Advanced or Metastatic Malignancy

Phase 1 Completed

Neoplasms

NCT02437227 2026-05-12

PanRAF

Phase 1 Completed

31 enrolled 16 charts

Melanoma, Neoplasms

NCT05076396 2026-05-11

PM14 Administered Intravenously to Patients With Advanced Solid Tumors

Phase 1 Completed

Neoplasms

NCT02211755 2026-04-28

Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid Tumors

Phase 1 Completed

LymphoidMyeloid

Lymphoma, Myelodysplastic Syndromes, Neoplasms

NCT02423057 2026-04-24

Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors

Phase 1 Completed

Neoplasms

NCT02379416 2026-04-21

Combination Nilotinib and Paclitaxel in Adults With Relapsed Solid Tumors

Phase 1 Completed

Neoplasms

NCT07450833 2026-04-20

BOOST

Phase 1 Completed

48 enrolled 38 charts

COVID-19, Neoplasms, Korsakoff Syndrome

NCT02379520 2026-04-15

HESTIA

Phase 1 Completed

Neoplasms, Recurrence

NCT03403049 2026-04-13

Carbon Ion Radiation Therapy for Locally Advanced Pancreatic Cancer

Phase 1 Completed

Gastrointestinal

Neoplasms, Pancreatic Neoplasms

NCT04488354 2026-04-08

Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T

Phase 1 Completed

LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Lymphoma, Follicular, Waldenstrom Macroglobulinemia, Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Hematologic Neoplasms, Lymphoma, Mantle-Cell

NCT03449381 2026-03-31

This Study Aims to Find the Best Dose of BI 907828 (Brigimadlin) in Patients With Different Types of Advanced Cancer (Solid Tumors)

Phase 1 Completed

Neoplasms

NCT03568058 2026-03-24

Personalized Immunotherapy in Adults With Advanced Cancers Immunotherapy in Adults With Advanced Cancers

Phase 1 Completed

25 enrolled 12 charts

Neoplasms

NCT05727839 2026-03-24

Study to Evaluate JCXH-211 as Monotherapy in Patients With Malignant Solid Tumors

Phase 1 Completed

Neoplasms, Skin Neoplasms

NCT06108479 2026-03-18

Study of DF6215 in Patients With Advanced Solid Tumors

Phase 1 Completed

DermatologicGenitourinaryGynecologicHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms

NCT06298357 2026-03-18

Virtual Reality Gaming for Exercise and Mindfulness Among Pediatric Cancer Rehabilitation

Phase 1 Completed

Neoplasms

NCT01374620 2026-03-16

PAL-ANGI2

Phase 1 Completed

Neoplasms

NCT06894771 2026-03-16

MK-4700-001

Phase 1 Completed

BreastDermatologicGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Melanoma, Neoplasms, Triple Negative Breast Neoplasms

NCT01046487 2026-03-13

PALANGI3

Phase 1 Completed

DermatologicGastrointestinalSarcoma

Uveal Melanoma, Chordoma, Carcinoma, Adenoid Cystic, Neoplasms, Desmoid Tumors, Dermatofibrosarcoma, Gastrointestinal Stromal Tumors

NCT03964233 2026-02-18

A Study in Patients With Different Types of Advanced Cancer (Solid Tumors) to Test Different Doses of BI 907828 (Brigimadlin) in Combination With BI 754091 (Ezabenlimab) and BI 754111 or BI 907828 (Brigimadlin) in Combination With BI 754091 (Ezabenlimab)

Phase 1 Completed

Neoplasms

NCT04397276 2026-02-17

A Study of JNJ-70218902 in Participants With Advanced Stage Solid Tumors

Phase 1 Completed

Neoplasms, Prostatic Neoplasms

NCT01534598 2026-02-10

FdCyd and THU for Advanced Solid Tumors

Phase 1 Completed

Neoplasms

NCT02989064 2026-02-04

MAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck Cancers

Phase 1 Completed

DermatologicGenitourinaryHead & Neck

Carcinoma, Transitional Cell, Head and Neck Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms

NCT04902313 2026-02-03

CROP

Phase 1 Completed

Anxiety Disorders, Depression, Neoplasms

NCT02952248 2026-01-27

A Trial to Find and Investigate a Safe Dose of a New Substance (BI 754091) for Patients With Solid Tumours

Phase 1 Completed

110 enrolled 22 charts

Neoplasms

NCT03156114 2026-01-26

This Study Tests the New Medicine BI 754111 Alone or in Combination With Another New Substance BI 754091 in Patients With Advanced Cancer. The Study Tests Different Doses to Find the Best Dose for Continuous Treatment.

Phase 1 Completed

172 enrolled 33 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT03510104 2026-01-08

Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid Tumors

Phase 1 Completed

Neoplasm Metastasis, Neoplasms, Neoplastic Processes, Pathologic Processes

NCT05678998 2026-01-06

WTX-330 in Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma

Phase 1 Completed

25 enrolled 31 charts

Lymphoma, Non-Hodgkin, Neoplasms

NCT01695005 2025-12-26

A Study of LY3039478 in Participants With Advanced Cancer

Phase 1 Completed

247 enrolled 53 charts

Lymphoma, Neoplasm Metastasis, Neoplasms

NCT04428788 2025-12-22

Study to Evaluate the Safety and Tolerability of CC-94676 in Participants With Metastatic Castration-Resistant Prostate Cancer

Phase 1 Completed

Neoplasms, Prostatic Neoplasms, Prostatic Neoplasms, Castration-Resistant

NCT03573310 2025-12-18

A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

Phase 1 Completed

LymphoidMyeloid

Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Neoplasms

NCT02275910 2025-12-16

Phase 1 Study of E7090 in Subjects With Solid Tumor

Phase 1 Completed

40 enrolled 30 charts

Neoplasms

NCT02860676 2025-12-15

Extension Study of UC-961 (Cirmtuzumab) for Patients With Chronic Lymphocytic Leukemia Treated Previously With UC-961

Phase 1 Completed

3 enrolled 8 charts

LymphoidOther hematologic neoplasm

Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell

NCT03595059 2025-12-10

A Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid Tumors

Phase 1 Completed

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Neoplasms, Small Cell Lung Carcinoma

NCT05740475 2025-12-09

A Study to Evaluate the Safety, Tolerability and Pharmacokinetic Properties of 9MW3811 in Healthy Subjects

Phase 1 Completed

Neoplasms, Pulmonary Fibrosis

NCT03307785 2025-11-25

Study of Niraparib, TSR-022, Bevacizumab, and Platinum-Based Doublet Chemotherapy in Combination With TSR-042

Phase 1 Completed

60 enrolled 91 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms

NCT05586321 2025-11-24

Study of Safety and Antitumor Activity of GEN1056 in Participants With Advanced Solid Tumors

Phase 1 Completed

Neoplasm Metastasis, Neoplasms

NCT02197234 2025-11-20

Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLC

Phase 1 Completed

52 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT02157883 2025-11-19

Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva)

Phase 1 Completed

39 enrolled 18 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT02812667 2025-11-12

Nivolumab in Combination With Plinabulin in Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC)

Phase 1 Completed

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms

NCT03486301 2025-11-12

EIK1001

Phase 1 Completed

Neoplasms

NCT04196530 2025-11-12

EIK1001

Phase 1 Completed

Neoplasms

NCT04840394 2025-11-12

Clinical Study of BDB018: Monotherapy and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Phase 1 Completed

Neoplasms

NCT03468426 2025-11-10

A Study to Test Different Doses of BI 836880 Combined With Ezabenlimab in Patients With Advanced Non-small Cell Lung Cancer Followed by Other Types of Advanced Solid Tumours

Phase 1 Completed

252 enrolled 47 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT04374877 2025-11-10

Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors

Phase 1 Completed

GastrointestinalGenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Neoplasms

NCT01582191 2025-10-27

Vandetanib and Everolimus in Treating Patients With Advanced or Metastatic Cancer

Phase 1 Completed

Neoplasm Metastasis, Neoplasms, Recurrence

NCT04824443 2025-10-27

Exercise Therapy in Cancer Patients Who Are Recovering From COVID-19

Phase 1 Completed

COVID-19, Motor Activity, Neoplasms, Coronavirus Infections