Clinical Trials Browser

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT07247110 2026-05-14

A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)

Phase 1 Recruiting

250 enrolled

Tumor-Agnostic

Neoplasms

NCT07525141 2026-05-14

A Study of JNJ-1761981 in Participants With Solid Tumors

Phase 1 Recruiting

66 enrolled

Tumor-Agnostic

Neoplasms

NCT07244835 2026-05-13

A Study of DEG6498 in Participants With Solid Tumors

Phase 1 Recruiting

100 enrolled

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Glioblastoma, Carcinoma, Hepatocellular, Kidney Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Neurofibrosarcoma

NCT06150157 2026-05-12

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

Phase 1 Recruiting

220 enrolled

Tumor-Agnostic

Neoplasms

NCT05647122 2026-05-11

EGRET

Phase 1 Recruiting

403 enrolled

GastrointestinalHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Neoplasms, Colorectal Neoplasms

NCT07217028 2026-05-11

Study Evaluating [18F]NOTA-ABY030 for Safety and Tolerability of Indeterminate Primary and/or Metastatic Disease in Head and Neck Squamous Cell Carcinoma

Phase 1 Recruiting

25 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Neoplasms

NCT07560943 2026-05-11

Safety and Tolerability of AI-Designed Pan-Cancer Neoantigen mRNA Vaccine (PAN-NeoVax) in Advanced Solid Tumors

Phase 1 Recruiting

9 enrolled

Tumor-Agnostic

Neoplasms

NCT07563972 2026-05-11

Intratumoral Macrophage Exosomes With Mechanobiological Reprogramming for Advanced Solid Tumors

Phase 1 Recruiting

9 enrolled

Tumor-Agnostic

Neoplasms

NCT05954312 2026-05-08

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

Phase 1 Recruiting

290 enrolled

Gastrointestinal

Adenocarcinoma Of Esophagus, Neoplasms

NCT06178614 2026-05-08

A Study of JNJ-87890387 for Advanced Solid Tumors

Phase 1 Recruiting

200 enrolled

Tumor-Agnostic

Neoplasms

NCT06311578 2026-05-08

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

Phase 1 Recruiting

126 enrolled

Tumor-Agnostic

Neoplasms

NCT07371104 2026-05-08

Bioequivalence Study of DWZ2501 in Patients With Advanced BRCA-mutated High-grade Ovarian Cancer

Phase 1 Recruiting

40 enrolled

Gynecologic

Neoplasms, Ovarian Neoplasms

NCT06835569 2026-05-06

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

Phase 1 Recruiting

188 enrolled

GastrointestinalThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07567222 2026-05-06

Clinical Study of Novel Therapeutic Vaccine for Advanced Solid Tumors

Phase 1 Recruiting

54 enrolled

Tumor-Agnostic

Neoplasms

NCT06132503 2026-05-04

Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors

Phase 1 Recruiting

110 enrolled

LymphoidSarcoma

Lymphoma, Neoplasms, Recurrence, Sarcoma

NCT04084067 2026-04-30

Indocyanine Green (ICG) Guided Tumor Resection

Phase 1 Recruiting

230 enrolled

CNSGastrointestinalGenitourinaryLymphoidSarcoma

Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Lymphoma, Neoplasms, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma

NCT07075185 2026-04-24

inMMyCAR

Phase 1 Recruiting

70 enrolled

LymphoidPlasma cell

Blood Protein Disorders, Disease, Hematologic Diseases, Immune System Diseases, Immunoproliferative Disorders, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Paraproteinemias, Vascular Diseases, Hemostatic Disorders

NCT06884618 2026-04-21

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

Phase 1 Recruiting

405 enrolled

Tumor-Agnostic

Neoplasms

NCT06997029 2026-04-21

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

Phase 1 Recruiting

234 enrolled

Tumor-Agnostic

Neoplasms

NCT06326411 2026-04-20

NST-628

Phase 1 Recruiting

230 enrolled

CNSDermatologic

Glioma, Melanoma, Neoplasms

NCT07538648 2026-04-20

A Phase II Clinical Study Evaluating the Effectiveness of Injectable NC527-X in Intraoperative Imaging for Patients With Solid Tumors

Phase 1 Recruiting

400 enrolled

Tumor-Agnostic

Neoplasms

NCT07127874 2026-04-17

A Study of PHN-012 in Patients With Advanced Solid Tumors

Phase 1 Recruiting

165 enrolled

GastrointestinalThoracic

Carcinoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms

NCT07258836 2026-04-17

A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer

Phase 1 Recruiting

41 enrolled

Tumor-Agnostic

Neoplasms

NCT06959706 2026-04-16

Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors

Phase 1 Recruiting

50 enrolled

Tumor-Agnostic

Carcinoma, Neoplasms

NCT07532018 2026-04-15

DXP-106

Phase 1 Recruiting

54 enrolled

Tumor-Agnostic

Neoplasms

NCT05382559 2026-04-14

A Study of ASP3082 in Adults With Advanced Solid Tumors

Phase 1 Recruiting

681 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT06253871 2026-04-13

A Phase 1/1b Study of IAM1363 in HER2 Cancers

Phase 1 Recruiting

383 enrolled

BreastCNSGastrointestinalThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Neoplasms, Stomach Neoplasms

NCT06333951 2026-04-13

Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).

Phase 1 Recruiting

500 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT06487624 2026-04-13

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

Phase 1 Recruiting

50 enrolled

Lymphoid

Camurati-Engelmann Syndrome, Hodgkin Disease, Neoplasms

NCT07424547 2026-04-07

Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors

Phase 1 Recruiting

386 enrolled

BreastGenitourinaryGynecologicThoracic

Breast Neoplasms, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Small Cell Lung Carcinoma

NCT06547840 2026-04-06

A Study of MOv18 IgE in Patients With Solid Tumours That Express Folate Receptor Alpha

Phase 1 Recruiting

45 enrolled

BreastGynecologic

Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06657144 2026-04-06

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

Phase 1 Recruiting

154 enrolled

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05544968 2026-04-03

Anti-CD30 biAb-AATC in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies

Phase 1 Recruiting

42 enrolled

LymphoidOther hematologic neoplasm

Hodgkin Disease, Leukemia, Lymphoma, Neoplasms, Recurrence, Lymphoma, Large-Cell, Anaplastic

NCT05752552 2026-04-03

Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients With Advanced or Refractory Solid Tumours

Phase 1 Recruiting

55 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT07144085 2026-04-03

Application of ⁶⁸Ga-FXX489 (NNS309) PET/CT Imaging in Diagnosis of Tumor Diseases.

Phase 1 Recruiting

30 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT06360354 2026-03-31

MTAPESTRY 103

Phase 1 Recruiting

350 enrolled

Gastrointestinal

Neoplasms, Pancreatic Neoplasms

NCT06687941 2026-03-27

A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors

Phase 1 Recruiting

70 enrolled

GastrointestinalThoracic

Simpson-Golabi-Behmel syndrome, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis, Neoplasms

NCT07103018 2026-03-23

STRIKE-001

Phase 1 Recruiting

144 enrolled

Genitourinary

Urogenital Diseases, Neoplasm Metastasis, Neoplasms, Neoplasms by Site, Prostatic Diseases, Prostatic Neoplasms, Urogenital Neoplasms, Male Urogenital Diseases

NCT05948865 2026-03-20

A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

Phase 1 Recruiting

132 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Neoplasms