Announcements Trials
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Phase

Phase 2/3 1

Status

Not yet recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Thoracic 1Plasma cell 1Other hematologic neoplasm 1Myeloid 1Lymphoid 1Head & Neck 1Gynecologic 1Gastrointestinal 1Endocrine 1CNS 1

Conditions

Melanoma 23Multiple Myeloma 9Colorectal Neoplasms 9Carcinoma, Non-Small-Cell Lung 9Glioma 8Thyroid Neoplasms 7Neoplasm Metastasis 7Hematologic Neoplasms 6Thyroid Carcinoma, Anaplastic 5Lymphoma 5Thyroid Cancer, Papillary 4Pancreatic Neoplasms 4Neurofibromatosis 1 4Neoplasms 4Lung Neoplasms 3Brain Neoplasms 3Astrocytoma 3Adenocarcinoma, Follicular 3Skin Neoplasms 2Recurrence 2Rectal Neoplasms 2Prostatic Neoplasms 2Ovarian Neoplasms 2Neurofibroma, Plexiform 2Leukemia, Myelomonocytic, Juvenile 2Histiocytosis, Langerhans-Cell 2Glioblastoma 2Colonic Neoplasms 2Advanced Solid Tumors 2Uveal Melanoma 1

Interventions

fludarabine 4Cyclophosphamide 4Cisplatin 4pembrolizumab 3atezolizumab 3Pemetrexed 3fludarabine phosphate 2entrectinib 2durvalumab 2cobimetinib 2capmatinib 2alectinib 2Whole-Body Irradiation 2Vemurafenib 2Tacrolimus 2Peripheral Blood Stem Cell Transplantation 2Patient Reported Outcome Measures 2Paclitaxel 2Nivolumab 2Mycophenolic Acid 2Mesna 2Melphalan 2Busulfan 2130-nm albumin-bound paclitaxel 2trametinib 1spartalizumab 1ruxolitinib 1repotrectinib 1pralsetinib 1ponatinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Neoplasms by Histologic Type × trametinib × 1 year × Clear all
NCT07440290 2026-02-27

DETERMINE

Cancer Research UK

Phase 2/3 Not yet recruiting
30 enrolled
CNSEndocrineGastrointestinalGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

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