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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Multiple Myeloma 13Leukemia, Myeloid, Acute 12Neoplasm Metastasis 11Lymphoma 11Pancreatic Neoplasms 9Burkitt Lymphoma 8Breast Neoplasms 8Myelodysplastic Syndromes 7Glioma 7Leukemia, Lymphocytic, Chronic, B-Cell 6Colorectal Neoplasms 6Triple Negative Breast Neoplasms 5Sarcoma 5Prostatic Neoplasms 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Neuroblastoma 5Lymphoma, Non-Hodgkin 5Central Nervous System Neoplasms 5Carcinoma, Renal Cell 5Wilms Tumor 4Squamous Cell Carcinoma of Head and Neck 4Rhabdoid Tumor 4Ovarian Neoplasms 4Oropharyngeal Neoplasms 4Neuroectodermal Tumors, Primitive, Peripheral 4Medulloblastoma 4Lymphoma, T-Cell 4Lung Neoplasms 4Histiocytosis, Langerhans-Cell 4Hepatoblastoma 4

Interventions

durvalumab 2ruxolitinib 1repotrectinib 1cemiplimab 1atezolizumab 1Pemetrexed 1Nivolumab 1Immunotherapy 1Docetaxel 1Cisplatin 1CPI-0610 1Biopsy 1Bevacizumab 1ALT-803 1130-nm albumin-bound paclitaxel 1

Date Range

30 days90 days1 yearAll

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Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Neoplasms by Histologic Type × Biopsy × 30 days × Clear all
NCT07416188 2026-06-05

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
40 enrolled
CNS

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Nerve Tissue, Recurrence, Central Nervous System Neoplasms

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