Announcements Trials
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Phase

Phase 1/2 1

Status

Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other neoplasm 1Other hematologic neoplasm 1Myeloid 1

Conditions

Primary Myelofibrosis 13Myeloproliferative Disorders 9Leukemia, Myeloid, Acute 8Thrombocythemia, Essential 6Polycythemia Vera 6Myelodysplastic Syndromes 5Lymphoma, T-Cell 4Leukemia 4Recurrence 3Neoplasms 3Graft vs Host Disease 3Myelodysplastic-Myeloproliferative Diseases 2Lymphoma, T-Cell, Cutaneous 2Lymphoma 2Leukemia, Prolymphocytic, T-Cell 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Hematologic Neoplasms 2Uveal Melanoma 1Thalassemia 1Targeted Therapy 1Prostatic Neoplasms 1Preleukemia 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precancerous Conditions 1Neoplasms by Histologic Type 1Mycosis Fungoides 1Multiple Myeloma 1Mesothelioma 1Melanoma 1Lymphoma, T-Cell, Peripheral 1

Interventions

fludarabine 2durvalumab 2Cyclophosphamide 2ruxolitinib 1repotrectinib 1ponatinib 1pembrolizumab 1gilteritinib 1fludarabine phosphate 1cemiplimab 1atezolizumab 1Whole-Body Irradiation 1Tacrolimus 1Peripheral Blood Stem Cell Transplantation 1Pemetrexed 1Patient Reported Outcome Measures 1Nivolumab 1Mycophenolic Acid 1Mesna 1Melphalan 1Immunotherapy 1Idarubicin 1Granulocyte Colony-Stimulating Factor 1Docetaxel 1Cytarabine 1Cisplatin 1CPI-0610 1Busulfan 1Bone Marrow Transplantation 1Biopsy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Neoplasms by Histologic Type × ruxolitinib × 90 days × Clear all
NCT02158858 2026-06-04

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Constellation Pharmaceuticals

Phase 1/2 Completed
336 enrolled 61 charts
MyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

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