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Phase

Phase 1/2 1

Status

Recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Neoplasm Metastasis 25Leukemia, Myeloid, Acute 25Breast Neoplasms 19Prostatic Neoplasms 16Myelodysplastic Syndromes 15Lymphoma, Large B-Cell, Diffuse 15Leukemia, Lymphocytic, Chronic, B-Cell 15Multiple Myeloma 14Lung Neoplasms 13Colorectal Neoplasms 12Carcinoma, Non-Small-Cell Lung 12Triple Negative Breast Neoplasms 11Precursor Cell Lymphoblastic Leukemia-Lymphoma 11Pancreatic Neoplasms 11Burkitt Lymphoma 11Neoplasms 9Lymphoma, Mantle-Cell 9Leukemia, Myelomonocytic, Chronic 9Ovarian Neoplasms 8Melanoma 8Lymphoma, T-Cell 8Stomach Neoplasms 7Carcinoma, Renal Cell 7Squamous Cell Carcinoma of Head and Neck 6Lymphoma, B-Cell 6Myeloproliferative Disorders 5Mouth Neoplasms 5Lymphoma 5Leukemia, Biphenotypic, Acute 5Fallopian Tube Neoplasms 5

Interventions

atezolizumab 3fludarabine 2entrectinib 2cobimetinib 2capmatinib 2alectinib 2Vemurafenib 2Pemetrexed 2Nivolumab 2Cisplatin 2spartalizumab 1repotrectinib 1pertuzumab 1lutetium Lu 177 dotatate 1gilteritinib 1enzalutamide 1durvalumab 1copper dotatate CU-64 1cemiplimab 1Trastuzumab 1Sodium Chloride 1Radiotherapy 1Radiosurgery 1Mitomycin 1Lutetium-177 1Lutetium 1Injections 1Idarubicin 1HuMax-IL8 1Granulocyte Colony-Stimulating Factor 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Recruiting × Neoplasms by Histologic Type × Biopsy × Clear all
NCT07416188 2026-06-05

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
40 enrolled
CNS

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms by Histologic Type, Neoplasms, Nerve Tissue, Recurrence, Central Nervous System Neoplasms

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