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Phase

Phase 2 9Phase 3 3Phase EARLY_PHASE1 2Phase 1 2Phase NA 1Phase 1/2 1

Status

Recruiting 2Completed 1

Sponsor Class

NETWORK 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3

Conditions

Breast Neoplasms 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 5Neuroblastoma 3Rhabdoid Tumor 2Leukemia, Myeloid, Acute 2Leukemia, Biphenotypic, Acute 2Ganglioneuroblastoma 2Central Nervous System Neoplasms 2Astrocytoma 2Oligodendroglioma 1Myelodysplastic Syndromes 1Medulloblastoma 1Leukemia 1Inflammatory Breast Neoplasms 1Graft vs Host Disease 1Choroid Plexus Neoplasms 1Brain Neoplasms 1

Interventions

Cyclophosphamide 21Carboplatin 17Etoposide 15Doxorubicin 14Vincristine 13Cisplatin 11Melphalan 10Filgrastim 10Radiotherapy 9Isotretinoin 8Topotecan 7Peripheral Blood Stem Cell Transplantation 6Granulocyte Colony-Stimulating Factor 6dinutuximab 5sargramostim 4etoposide phosphate 4Neoadjuvant Therapy 4Magnetic Resonance Spectroscopy 4Busulfan 4Vindesine 3Thiotepa 3Platinum 3Ifosfamide 3Colony-Stimulating Factors 3Chemotherapy, Adjuvant 3Biopsy 33-Iodobenzylguanidine 31,2-diaminocyclohexaneplatinum II citrate 3liposomal amphotericin B 2fluorodopa F 18 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 3 × Neuroblastoma × Thiotepa × Clear all
NCT06172296 2026-05-27

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

National Cancer Institute (NCI)

Phase 3 Recruiting
478 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Children's Oncology Group

Phase 3 Recruiting
750 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT00567567 2022-04-28

Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma

Children's Oncology Group

Phase 3 Completed
665 enrolled 26 charts
CNS

Neuroblastoma

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